Mechanisms of thrombopoiesis

Megakaryocytes (MKs) expand and differentiate over several days in response to thrombopoietin (Tpo) before releasing innumerable blood platelets. The final steps in platelet assembly and release represent a unique cellular transformation that is orchestrated by a range of transcription factors, sign...

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of thrombosis and haemostasis 2005-08, Vol.3 (8), p.1717-1724
Hauptverfasser:	SCHULZE, H., SHIVDASANI, R. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Platelets - metabolism bone marrow cell interactions Cell Differentiation Chemokine CXCL12 Chemokines, CXC - metabolism Cytoplasm - metabolism Genome Humans megakaryocytes Megakaryocytes - immunology Megakaryocytes - metabolism Microtubules - metabolism platelet biogenesis platelet release Protein Binding Proteomics Signal Transduction Thrombopoiesis - physiology transcription factors Transcription Factors - metabolism Transcription, Genetic
Online-Zugang:	Volltext
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