PER2 controls circadian periods through nuclear localization in the suprachiasmatic nucleus

Molecular circadian clock regulation engages a negative feedback loop comprising components of the negative limb, PERs and CRYs. In addition to the rhythmic transcriptional regulation of clock genes, controlled subcellular localization might contribute to the molecular mechanism of the mammalian cir...

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Veröffentlicht in:	Genes to cells : devoted to molecular & cellular mechanisms 2007-11, Vol.12 (11), p.1225-1234
Hauptverfasser:	Miyazaki, Koyomi, Wakabayashi, Miyuki, Chikahisa, Sachiko, Sei, Hiroyoshi, Ishida, Norio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Temperature Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Cell Nucleus - chemistry Cell Nucleus - metabolism Cercopithecus aethiops Circadian Rhythm - physiology COS Cells Cryptochromes Flavoproteins - analysis Flavoproteins - genetics Flavoproteins - metabolism Mice Models, Biological Nuclear Localization Signals Nuclear Proteins - genetics Nuclear Proteins - metabolism Period Circadian Proteins Rats RNA, Messenger - metabolism Suprachiasmatic Nucleus - metabolism
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