Variable extent of platelet responsiveness to clopidogrel inhibition: "clopidogrel resistance"?

During percutaneous coronary angioplasty, platelet inhibition by clopidogrel and aspirin has drastically decreased the risk of thrombotic occlusion of the stented vessels. However, despite the widespread use of these drugs, the incidence of acute or subacute stent thrombosis remains elevated, concer...

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Veröffentlicht in:	Annales de cardiologie et d'angéiologie 2005-08, Vol.54 (4), p.194-200
Hauptverfasser:	Morel, O, Ohlmann, P, Jesel, L, Morel, N, Ridard, C, Faure, A, Grunebaum, L, Toti, F, Bareiss, P
Format:	Artikel
Sprache:	fre
Schlagworte:	Angioplasty, Balloon Dose-Response Relationship, Drug Drug Resistance Humans Platelet Aggregation Inhibitors - therapeutic use Polymorphism, Genetic Receptors, Purinergic P2 - genetics Thrombosis - prevention & control Ticlopidine - analogs & derivatives Ticlopidine - therapeutic use
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