Serum levels and genetic variation of TGF-beta1 are not associated with Alzheimer's disease

As transforming growth factor-beta1 (TGF-beta1) determines important neurotrophic and neuroprotective actions, we postulated serum TGF-beta1 levels could be low in Alzheimer's disease (AD), and TGF-beta1 genetic variation could be associated with AD risk through modulating serum TGF-beta1 level...

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Veröffentlicht in:	Acta neurologica Scandinavica 2007-12, Vol.116 (6), p.409-412
Hauptverfasser:	Rodríguez-Rodríguez, E, Sánchez-Juan, P, Mateo, I, Llorca, J, Infante, J, García-Gorostiaga, I, Berciano, J, Combarros, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - blood Alzheimer Disease - diagnosis Alzheimer Disease - genetics DNA Mutational Analysis Female Gene Frequency - genetics Genetic Markers - genetics Genetic Predisposition to Disease - genetics Genetic Testing Genetic Variation - genetics Genotype Humans Male Middle Aged Polymorphism, Genetic - genetics Predictive Value of Tests Risk Factors Sensitivity and Specificity Transforming Growth Factor beta1 - blood Transforming Growth Factor beta1 - genetics
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