Choosing the correct functional assay: A comprehensive assessment of functional tests in the rat
While there are several ways to quantify peripheral nerve regeneration; the true measure of successful outcome is functional recovery. Functional tests are relatively easily conducted in human subjects; however it is more difficult in a laboratory animal. The laboratory rat is an excellent animal mo...
Gespeichert in:
| Veröffentlicht in: | Behavioural brain research 2005-09, Vol.163 (2), p.143-158 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 158 |
|---|---|
| container_issue | 2 |
| container_start_page | 143 |
| container_title | Behavioural brain research |
| container_volume | 163 |
| creator | Nichols, Chris M. Myckatyn, Terence M. Rickman, Susan R. Fox, Ida K. Hadlock, Tessa Mackinnon, Susan E. |
| description | While there are several ways to quantify peripheral nerve regeneration; the true measure of successful outcome is functional recovery. Functional tests are relatively easily conducted in human subjects; however it is more difficult in a laboratory animal. The laboratory rat is an excellent animal model of peripheral nerve injury and has been used extensively in the field of peripheral nerve research. Due to the intense interest in the rat as an experimental model, functional assays have been reported. In an effort to provide a resource to which investigators can refer when considering the most appropriate functional assay for a given experiment, the authors have compiled and tabulated the available functional tests applicable to various models of rat nerve injury. |
| doi_str_mv | 10.1016/j.bbr.2005.05.003 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68477974</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0166432805002068</els_id><sourcerecordid>68477974</sourcerecordid><originalsourceid>FETCH-LOGICAL-c443t-da678ec714b41e2c295cc33f7c6efb5307dcb14e7ec89494e71cf511ad1adbf43</originalsourceid><addsrcrecordid>eNqF0UFvFCEUB3BibOy2-gG8mLnobbYwwDDoqdlobdKkFz0jwzxcNjOw8mab9NuXcTepJ5u8BAI_Xl74E_Ke0TWjrL3arfs-rxtK5Xopyl-RFetUUysp9GuyKqatBW-6c3KBuKOUCirZG3LOpFaatd2K_NpsU8IQf1fzFiqXcgY3V_4Q3RxStGNlEe3j5-q63E37DFuIGB5gOQbECeJcJf-vnwFnrEL82y_b-S0583ZEeHdaL8nPb19_bL7Xd_c3t5vru9oJwed6sK3qwCkmesGgcY2WznHulWvB95JTNbieCVDgOi102TDnJWN2KNV7wS_Jp2PffU5_DmUIMwV0MI42QjqgaTuhlFYvw4Z2DZeavgiZatviugLZEbqcEDN4s89hsvnRMGqWoMzOlKDMEpRZivLy5sOp-aGfYHh-cUqmgI8nYNHZ0WcbXcBnp6ikqtHFfTk6KJ_7ECAbdAGigyEsUZohhf-M8QTULLGX</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>17665908</pqid></control><display><type>article</type><title>Choosing the correct functional assay: A comprehensive assessment of functional tests in the rat</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Nichols, Chris M. ; Myckatyn, Terence M. ; Rickman, Susan R. ; Fox, Ida K. ; Hadlock, Tessa ; Mackinnon, Susan E.</creator><creatorcontrib>Nichols, Chris M. ; Myckatyn, Terence M. ; Rickman, Susan R. ; Fox, Ida K. ; Hadlock, Tessa ; Mackinnon, Susan E.</creatorcontrib><description>While there are several ways to quantify peripheral nerve regeneration; the true measure of successful outcome is functional recovery. Functional tests are relatively easily conducted in human subjects; however it is more difficult in a laboratory animal. The laboratory rat is an excellent animal model of peripheral nerve injury and has been used extensively in the field of peripheral nerve research. Due to the intense interest in the rat as an experimental model, functional assays have been reported. In an effort to provide a resource to which investigators can refer when considering the most appropriate functional assay for a given experiment, the authors have compiled and tabulated the available functional tests applicable to various models of rat nerve injury.</description><identifier>ISSN: 0166-4328</identifier><identifier>EISSN: 1872-7549</identifier><identifier>DOI: 10.1016/j.bbr.2005.05.003</identifier><identifier>PMID: 15979168</identifier><identifier>CODEN: BBREDI</identifier><language>eng</language><publisher>Shannon: Elsevier B.V</publisher><subject>Animals ; Biological and medical sciences ; Biomechanical Phenomena - methods ; Extremities - physiopathology ; Forelimb ; Functional test ; Fundamental and applied biological sciences. Psychology ; Hind limb ; Humans ; Motor ; Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration ; Nerve ; Nerve Regeneration - physiology ; Peripheral Nervous System Diseases - physiopathology ; Rat ; Rats ; Recovery of Function - physiology ; Sensation - physiology ; Sensory ; Vertebrates: nervous system and sense organs ; Vibrissae ; Vibrissae - innervation ; Vibrissae - physiology</subject><ispartof>Behavioural brain research, 2005-09, Vol.163 (2), p.143-158</ispartof><rights>2005 Elsevier B.V.</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443t-da678ec714b41e2c295cc33f7c6efb5307dcb14e7ec89494e71cf511ad1adbf43</citedby><cites>FETCH-LOGICAL-c443t-da678ec714b41e2c295cc33f7c6efb5307dcb14e7ec89494e71cf511ad1adbf43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.bbr.2005.05.003$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,27926,27927,45997</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17050729$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15979168$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nichols, Chris M.</creatorcontrib><creatorcontrib>Myckatyn, Terence M.</creatorcontrib><creatorcontrib>Rickman, Susan R.</creatorcontrib><creatorcontrib>Fox, Ida K.</creatorcontrib><creatorcontrib>Hadlock, Tessa</creatorcontrib><creatorcontrib>Mackinnon, Susan E.</creatorcontrib><title>Choosing the correct functional assay: A comprehensive assessment of functional tests in the rat</title><title>Behavioural brain research</title><addtitle>Behav Brain Res</addtitle><description>While there are several ways to quantify peripheral nerve regeneration; the true measure of successful outcome is functional recovery. Functional tests are relatively easily conducted in human subjects; however it is more difficult in a laboratory animal. The laboratory rat is an excellent animal model of peripheral nerve injury and has been used extensively in the field of peripheral nerve research. Due to the intense interest in the rat as an experimental model, functional assays have been reported. In an effort to provide a resource to which investigators can refer when considering the most appropriate functional assay for a given experiment, the authors have compiled and tabulated the available functional tests applicable to various models of rat nerve injury.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Biomechanical Phenomena - methods</subject><subject>Extremities - physiopathology</subject><subject>Forelimb</subject><subject>Functional test</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hind limb</subject><subject>Humans</subject><subject>Motor</subject><subject>Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration</subject><subject>Nerve</subject><subject>Nerve Regeneration - physiology</subject><subject>Peripheral Nervous System Diseases - physiopathology</subject><subject>Rat</subject><subject>Rats</subject><subject>Recovery of Function - physiology</subject><subject>Sensation - physiology</subject><subject>Sensory</subject><subject>Vertebrates: nervous system and sense organs</subject><subject>Vibrissae</subject><subject>Vibrissae - innervation</subject><subject>Vibrissae - physiology</subject><issn>0166-4328</issn><issn>1872-7549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0UFvFCEUB3BibOy2-gG8mLnobbYwwDDoqdlobdKkFz0jwzxcNjOw8mab9NuXcTepJ5u8BAI_Xl74E_Ke0TWjrL3arfs-rxtK5Xopyl-RFetUUysp9GuyKqatBW-6c3KBuKOUCirZG3LOpFaatd2K_NpsU8IQf1fzFiqXcgY3V_4Q3RxStGNlEe3j5-q63E37DFuIGB5gOQbECeJcJf-vnwFnrEL82y_b-S0583ZEeHdaL8nPb19_bL7Xd_c3t5vru9oJwed6sK3qwCkmesGgcY2WznHulWvB95JTNbieCVDgOi102TDnJWN2KNV7wS_Jp2PffU5_DmUIMwV0MI42QjqgaTuhlFYvw4Z2DZeavgiZatviugLZEbqcEDN4s89hsvnRMGqWoMzOlKDMEpRZivLy5sOp-aGfYHh-cUqmgI8nYNHZ0WcbXcBnp6ikqtHFfTk6KJ_7ECAbdAGigyEsUZohhf-M8QTULLGX</recordid><startdate>20050908</startdate><enddate>20050908</enddate><creator>Nichols, Chris M.</creator><creator>Myckatyn, Terence M.</creator><creator>Rickman, Susan R.</creator><creator>Fox, Ida K.</creator><creator>Hadlock, Tessa</creator><creator>Mackinnon, Susan E.</creator><general>Elsevier B.V</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope><scope>7X8</scope></search><sort><creationdate>20050908</creationdate><title>Choosing the correct functional assay: A comprehensive assessment of functional tests in the rat</title><author>Nichols, Chris M. ; Myckatyn, Terence M. ; Rickman, Susan R. ; Fox, Ida K. ; Hadlock, Tessa ; Mackinnon, Susan E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c443t-da678ec714b41e2c295cc33f7c6efb5307dcb14e7ec89494e71cf511ad1adbf43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Biomechanical Phenomena - methods</topic><topic>Extremities - physiopathology</topic><topic>Forelimb</topic><topic>Functional test</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hind limb</topic><topic>Humans</topic><topic>Motor</topic><topic>Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration</topic><topic>Nerve</topic><topic>Nerve Regeneration - physiology</topic><topic>Peripheral Nervous System Diseases - physiopathology</topic><topic>Rat</topic><topic>Rats</topic><topic>Recovery of Function - physiology</topic><topic>Sensation - physiology</topic><topic>Sensory</topic><topic>Vertebrates: nervous system and sense organs</topic><topic>Vibrissae</topic><topic>Vibrissae - innervation</topic><topic>Vibrissae - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nichols, Chris M.</creatorcontrib><creatorcontrib>Myckatyn, Terence M.</creatorcontrib><creatorcontrib>Rickman, Susan R.</creatorcontrib><creatorcontrib>Fox, Ida K.</creatorcontrib><creatorcontrib>Hadlock, Tessa</creatorcontrib><creatorcontrib>Mackinnon, Susan E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Behavioural brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nichols, Chris M.</au><au>Myckatyn, Terence M.</au><au>Rickman, Susan R.</au><au>Fox, Ida K.</au><au>Hadlock, Tessa</au><au>Mackinnon, Susan E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Choosing the correct functional assay: A comprehensive assessment of functional tests in the rat</atitle><jtitle>Behavioural brain research</jtitle><addtitle>Behav Brain Res</addtitle><date>2005-09-08</date><risdate>2005</risdate><volume>163</volume><issue>2</issue><spage>143</spage><epage>158</epage><pages>143-158</pages><issn>0166-4328</issn><eissn>1872-7549</eissn><coden>BBREDI</coden><abstract>While there are several ways to quantify peripheral nerve regeneration; the true measure of successful outcome is functional recovery. Functional tests are relatively easily conducted in human subjects; however it is more difficult in a laboratory animal. The laboratory rat is an excellent animal model of peripheral nerve injury and has been used extensively in the field of peripheral nerve research. Due to the intense interest in the rat as an experimental model, functional assays have been reported. In an effort to provide a resource to which investigators can refer when considering the most appropriate functional assay for a given experiment, the authors have compiled and tabulated the available functional tests applicable to various models of rat nerve injury.</abstract><cop>Shannon</cop><pub>Elsevier B.V</pub><pmid>15979168</pmid><doi>10.1016/j.bbr.2005.05.003</doi><tpages>16</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0166-4328 |
| ispartof | Behavioural brain research, 2005-09, Vol.163 (2), p.143-158 |
| issn | 0166-4328 1872-7549 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68477974 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Animals Biological and medical sciences Biomechanical Phenomena - methods Extremities - physiopathology Forelimb Functional test Fundamental and applied biological sciences. Psychology Hind limb Humans Motor Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Nerve Nerve Regeneration - physiology Peripheral Nervous System Diseases - physiopathology Rat Rats Recovery of Function - physiology Sensation - physiology Sensory Vertebrates: nervous system and sense organs Vibrissae Vibrissae - innervation Vibrissae - physiology |
| title | Choosing the correct functional assay: A comprehensive assessment of functional tests in the rat |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T12%3A37%3A52IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Choosing%20the%20correct%20functional%20assay:%20A%20comprehensive%20assessment%20of%20functional%20tests%20in%20the%20rat&rft.jtitle=Behavioural%20brain%20research&rft.au=Nichols,%20Chris%20M.&rft.date=2005-09-08&rft.volume=163&rft.issue=2&rft.spage=143&rft.epage=158&rft.pages=143-158&rft.issn=0166-4328&rft.eissn=1872-7549&rft.coden=BBREDI&rft_id=info:doi/10.1016/j.bbr.2005.05.003&rft_dat=%3Cproquest_cross%3E68477974%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=17665908&rft_id=info:pmid/15979168&rft_els_id=S0166432805002068&rfr_iscdi=true |