A surface 75-kDa protein with acid phosphatase activity recognized by monoclonal antibodies that inhibit Paracoccidioides brasiliensis growth

Paracoccidioides brasiliensis is a thermo-dimorphic fungus responsible for paracoccidioidomycosis (PCM), a systemic granulomatous mycosis prevalent in Latin America. The fungus releases many antigens which may be transiently bound to its cell surface. Some of them may show enzymatic functions essent...

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Veröffentlicht in:	Microbes and infection 2007-10, Vol.9 (12), p.1484-1492
Hauptverfasser:	Xander, Patrícia, Vigna, Ana Flávia, Feitosa, Luciano dos Santos, Pugliese, Lívia, Bailão, Alexandre Melo, Soares, Célia Maria de Almeida, Mortara, Renato Arruda, Mariano, Mario, Lopes, José Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid phosphatase Acid Phosphatase - immunology Acid Phosphatase - metabolism Amino Acid Sequence Animals Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - immunology Antigens, Fungal - immunology Antigens, Fungal - metabolism Applied microbiology Biological and medical sciences Fundamental and applied biological sciences. Psychology Fungal Proteins - immunology Fungal Proteins - metabolism Immunization, Passive Macrophages, Peritoneal - microbiology Male Membrane Proteins - immunology Membrane Proteins - metabolism Mice Mice, Inbred BALB C Microbiology Miscellaneous Molecular Sequence Data Monoclonal antibodies Mycology P. brasiliensis Paracoccidioides - growth & development Paracoccidioides - immunology Paracoccidioides brasiliensis Paracoccidioidomycosis - immunology Paracoccidioidomycosis - microbiology Paracoccidioidomycosis - prevention & control Phagocytosis Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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