A High Throughput Screen to Identify Substrates for the Ubiquitin Ligase Rsp5

Ubiquitin-protein ligases (E3s) are implicated in various human disorders and are attractive targets for therapeutic intervention. Although most cellular proteins are ubiquitinated, ubiquitination cannot be linked directly to a specific E3 for a large fraction of these proteins, and the substrates o...

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Veröffentlicht in:	The Journal of biological chemistry 2005-08, Vol.280 (33), p.29470-29478
Hauptverfasser:	Kus, Bart, Gajadhar, Aaron, Stanger, Karen, Cho, Rob, Sun, Warren, Rouleau, Nathalie, Lee, Tammy, Chan, Donovan, Wolting, Cheryl, Edwards, Aled, Bosse, Roger, Rotin, Daniela
Format:	Artikel
Sprache:	eng
Schlagworte:	Endosomal Sorting Complexes Required for Transport Luminescent Measurements Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins - metabolism Ubiquitin - metabolism Ubiquitin-Protein Ligase Complexes - metabolism
Online-Zugang:	Volltext
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