Usnea barbata extract prevents ultraviolet-B induced prostaglandin E2 synthesis and COX-2 expression in HaCaT keratinocytes

Usnea barbata and its major constituent usnic acid are potent antimicrobial agents. Here, we have investigated anti-inflammatory properties of an U. barbata extract (UBE) containing 4% usnic acid in an ultraviolet-B (UVB) model with HaCaT keratinocytes. UVB irradiation induced PGE(2) production and...

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Veröffentlicht in:	Journal of photochemistry and photobiology. B, Biology Biology, 2007-11, Vol.89 (1), p.9-14
Hauptverfasser:	Engel, K, Schmidt, U, Reuter, J, Weckesser, S, Simon-Haarhaus, B, Schempp, C M
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Extracts - pharmacology Cells, Cultured Cyclooxygenase 2 - biosynthesis Cyclooxygenase 2 - metabolism Dinoprostone - biosynthesis Dose-Response Relationship, Drug Gene Expression Regulation, Enzymologic - drug effects Gene Expression Regulation, Enzymologic - radiation effects Keratinocytes - drug effects Keratinocytes - enzymology Keratinocytes - metabolism Keratinocytes - radiation effects Ultraviolet Rays Up-Regulation - drug effects Up-Regulation - radiation effects Usnea - chemistry
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