Safety of the RTS,S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

Summary Background Malaria remains a leading global health problem that requires the improved use of existing interventions and the accelerated development of new control methods. We aimed to assess the safety, immunogenicity, and initial efficacy of the malaria vaccine RTS,S/AS02D in infants in Afr...

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Veröffentlicht in:	The Lancet (British edition) 2007-11, Vol.370 (9598), p.1543-1551
Hauptverfasser:	Aponte, John J, MD, Aide, Pedro, MD, Renom, Montse, MD, Mandomando, Inacio, VetMed, Bassat, Quique, MD, Sacarlal, Jahit, MD, Manaca, M Nelia, BSc, Lafuente, Sarah, MD, Barbosa, Arnoldo, MD, Leach, Amanda, MRCPCH, Lievens, Marc, MSc, Vekemans, Johan, MD, Sigauque, Betuel, MD, Dubois, Marie-Claude, MSc, Demoitié, Marie-Ange, MSc, Sillman, Marla, MSc, Savarese, Barbara, RN, McNeil, John G, MD, Macete, Eusebio, MD, Ballou, W Ripley, MD, Cohen, Joe, PhD, Alonso, Pedro L, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Protozoan - blood Double-Blind Method Female Global health Hospitals Humans Immunization Immunization Schedule Immunogenicity Infant Infants Internal Medicine Malaria Malaria - prevention & control Malaria Vaccines - administration & dosage Malaria Vaccines - adverse effects Male Medical research Mozambique Plasmodium falciparum - immunology Public health Safety Vaccines Vector-borne diseases Womens health
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