Familial Mediterranean fever and mesangial proliferative glomerulonephritis: report of a case and review of the literature
In familial Mediterranean fever (FMF), a genetically inherited disease characterized by fever and serositis, renal involvement is mainly AA amyloidosis. We report a patient with FMF who developed mesangial proliferative glomerulonephritis; presumably in response to colchicine treatment, the activity...
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| Veröffentlicht in: | Pediatric nephrology (Berlin, West) West), 2005-09, Vol.20 (9), p.1352-1354 |
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| container_title | Pediatric nephrology (Berlin, West) |
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| creator | Cagdas, Deniz N Gucer, Safak Kale, Gülsev Duzova, Ali Ozen, Seza |
| description | In familial Mediterranean fever (FMF), a genetically inherited disease characterized by fever and serositis, renal involvement is mainly AA amyloidosis. We report a patient with FMF who developed mesangial proliferative glomerulonephritis; presumably in response to colchicine treatment, the activity of the disease decreased and renal function tests and urinary findings normalized. This report emphasizes the concurrent existence of mesangial proliferative glomerulonephritis with FMF in the absence of renal amyloidosis. Due to increased inflammatory response observed in FMF, immunologic glomerular injury, a common cause of glomerulonephritis, may occur more frequently in patients with FMF. |
| doi_str_mv | 10.1007/s00467-005-1991-9 |
| format | Article |
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We report a patient with FMF who developed mesangial proliferative glomerulonephritis; presumably in response to colchicine treatment, the activity of the disease decreased and renal function tests and urinary findings normalized. This report emphasizes the concurrent existence of mesangial proliferative glomerulonephritis with FMF in the absence of renal amyloidosis. 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We report a patient with FMF who developed mesangial proliferative glomerulonephritis; presumably in response to colchicine treatment, the activity of the disease decreased and renal function tests and urinary findings normalized. This report emphasizes the concurrent existence of mesangial proliferative glomerulonephritis with FMF in the absence of renal amyloidosis. Due to increased inflammatory response observed in FMF, immunologic glomerular injury, a common cause of glomerulonephritis, may occur more frequently in patients with FMF.</abstract><cop>Germany</cop><pub>Springer</pub><pmid>15971069</pmid><doi>10.1007/s00467-005-1991-9</doi><tpages>3</tpages></addata></record> |
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| subjects | Adolescent Care and treatment Case studies Causes of Colchicine Colchicine - therapeutic use Complications and side effects Diagnosis Dosage and administration Drug therapy Familial Mediterranean fever Familial Mediterranean Fever - complications Glomerulonephritis Glomerulonephritis, Membranoproliferative - drug therapy Glomerulonephritis, Membranoproliferative - etiology Humans Male Renal Agents - therapeutic use Treatment Outcome |
| title | Familial Mediterranean fever and mesangial proliferative glomerulonephritis: report of a case and review of the literature |
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