Neuroprotective effect of mivazerol, an alpha 2-agonist, after transient forebrain ischemia in rats

We examined whether mivazerol, an alpha2-agonist, had neuroprotective effects after transient forebrain ischemia in rats. Male Sprague-Dawley rats, anesthetized with halothane, were assigned to one of four groups (n=10 each): control (C, normal saline) and mivazerol 10 microg/kg (M10), 20 microg/kg...

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Veröffentlicht in:	Acta anaesthesiologica Scandinavica 2005-09, Vol.49 (8), p.1117-1123
Hauptverfasser:	Kimura, T, Sato, M, Nishikawa, T, Tanaka, M, Tobe, Y, Masaki, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - pharmacology Animals Blood Gas Analysis Blood Glucose - drug effects Blood Pressure - drug effects Body Temperature - drug effects Disease Models, Animal Heart Rate - drug effects Hydrogen-Ion Concentration - drug effects Imidazoles - pharmacology Ischemic Attack, Transient - drug therapy Ischemic Attack, Transient - mortality Ischemic Attack, Transient - physiopathology Male Neuroprotective Agents - pharmacology Rats Rats, Sprague-Dawley Survival Rate Time Factors
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