Rituximab anti-B-cell therapy in systemic lupus erythematosus: pointing to the future

PURPOSE OF REVIEWTo discuss the clinical effects and the immunologic consequences of transient B-cell depletion using the anti-CD20 monoclonal antibody rituximab in systemic lupus erythematosus. RECENT FINDINGSA total of 100 rituximab-treated patients with severe disease, refractory to major immunos...

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Veröffentlicht in:	Current opinion in rheumatology 2005-09, Vol.17 (5), p.550-557
Hauptverfasser:	Sfikakis, Petros P, Boletis, John N, Tsokos, George C
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Murine-Derived B-Lymphocytes - immunology Humans Immunologic Factors - therapeutic use Lupus Erythematosus, Systemic - drug therapy Lupus Erythematosus, Systemic - immunology Rituximab
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