Early and Dynamic Polarization of T Cell Membrane Rafts and Constituents Prior to TCR Stop Signals

Polarization of membrane rafts and signaling proteins to form an immunological synapse is a hallmark of T cell stimulation. However, the kinetics of raft polarization and associated proteins in relation to the initial contact of the T cell with the APC are poorly defined. We addressed this question...

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Veröffentlicht in:The Journal of immunology (1950) 2007-11, Vol.179 (10), p.6845-6855
Hauptverfasser: Van Komen, Jeffrey S, Mishra, Sudha, Byrum, Jennifer, Chichili, Gurunadh R, Yaciuk, Jane C, Farris, A. Darise, Rodgers, William
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Sprache:eng
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