Quantitative Trait Loci for Glomerulosclerosis, Kidney Weight and Body Weight in the Focal Glomerulosclerosis Mouse Model

In 183 male progeny derived from a backcross between the FGS/Kist strain, a new mouse model for focal glomerulosclerosis (FGS) in humans, and the standard normal strain, C57BL/6J, we performed a genome-wide scan for quantitative trait loci (QTLs) affecting the glomerulosclerosis index (GSI) based on...

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Veröffentlicht in:	Experimental Animals 2005, Vol.54(4), pp.319-325
Hauptverfasser:	KIM, Eun-Hee, LEE, Chul-Ho, HYUN, Byung-Hwa, SUH, Jun-Gyo, OH, Yang-Seok, NAMIKAWA, Takao, ISHIKAWA, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals body weight Body Weight - genetics Disease Models, Animal Epistasis, Genetic focal glomerulosclerosis Glomerulosclerosis, Focal Segmental - genetics Glomerulosclerosis, Focal Segmental - pathology Homozygote Kidney - pathology kidney weight Male Mice Mice, Inbred C57BL mouse Organ Size - genetics Phenotype Quantitative Trait Loci quantitative trait locus
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