Interrelationships among chromosome aneuploidy, promoter hypermethylation, and protein expression of the CDKN2A gene in individuals from northern Brazil with gastric adenocarcinoma

Abstract Numerical alterations of chromosome 9, the status of promoter methylation and protein expression of the CDKN2A gene (aliases include p16 and p16INK4a ), the possible association with gain of chromosome X, and the interrelation of these findings with clinic and pathological characteristics w...

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Veröffentlicht in:	Cancer genetics and cytogenetics 2007-11, Vol.179 (1), p.45-51
Hauptverfasser:	Guimarães, Adriana Costa, Lima, Eleonidas Moura, Khayat, André Salim, Girão Faria, Mário Henrique, Barem Rabenhorst, Silvia Helena, Pitombeira, Márcia Valéria, Assumpção, Paulo Pimentel, de Oliveira Bahia, Marcelo, Lima de Lima, Patrícia Danielle, de Arruda Cardoso Smith, Marília, Burbano, Rommel Rodríguez
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - pathology Adult Aged Aneuploidy Chromosomes, Human, Pair 9 Chromosomes, Human, X Cyclin-Dependent Kinase Inhibitor p16 - genetics Cyclin-Dependent Kinase Inhibitor p16 - metabolism DNA Methylation Female Genes, p16 Hematology, Oncology and Palliative Medicine Humans In Situ Hybridization, Fluorescence Male Medical Education Middle Aged Polymerase Chain Reaction Promoter Regions, Genetic Stomach Neoplasms - genetics Stomach Neoplasms - metabolism Stomach Neoplasms - pathology
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