Selection of Smart Aptamers by Equilibrium Capillary Electrophoresis of Equilibrium Mixtures (ECEEM)

We coin a term of “smart aptamers”, which describes aptamers with predefined binding parameters of their interaction with the target. Here, we introduce a method for selection of smart aptamers with predefined values of K d:  equilibrium capillary electrophoresis of equilibrium mixtures (ECEEM). Con...

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Veröffentlicht in:	Journal of the American Chemical Society 2005-08, Vol.127 (32), p.11224-11225
Hauptverfasser:	Drabovich, Andrei, Berezovski, Maxim, Krylov, Sergey N
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Base Sequence Biological and medical sciences DNA - chemistry Electrophoresis, Capillary Fundamental and applied biological sciences. Psychology General aspects, investigation methods Molecular Sequence Data Nucleic Acid Conformation Nucleic acids Oligonucleotides - chemistry Oligonucleotides - isolation & purification RNA - chemistry
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