Effects of dehydroepiandrosterone, Premarin and Acolbifene on histomorphology and sex steroid receptors in the rat vagina

To assess the specific estrogenic and/or androgenic effects of a potential novel hormone replacement therapy, we have examined the morphology of the rat vagina 9 months after ovariectomy (OVX) and treatment of OVX animals with dehydroepiandrosterone (DHEA), conjugated estrogens Premarin and the sele...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 2005-07, Vol.96 (2), p.201-215
Hauptverfasser:	Berger, L., El-Alfy, M., Martel, C., Labrie, F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acolbifene Androgen receptor Animals Antiestrogen Biological and medical sciences Dehydroepiandrosterone - pharmacology DHEA EM-652 Estrogen receptor Estrogens, Conjugated (USP) - pharmacology Estrus Female Fundamental and applied biological sciences. Psychology Hormone replacement therapy In Vitro Techniques Intracrinology Menopause Organ Size Ovariectomy Piperidines - pharmacology Proestrus Progesterone receptor Rats Rats, Sprague-Dawley Receptors, Estrogen - drug effects Receptors, Estrogen - physiology SERM Sexual dysfunction Vagina Vagina - anatomy & histology Vagina - cytology Vagina - drug effects Vagina - physiology Vertebrates: endocrinology
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