Controversies in nephrology: Response to ‘renal albumin handling, facts, and artifacts’

For 40 years indirect measurements of the glomerular sieving coefficient of albumin yielded very low values. The first direct measurement by 2-photon microscopy by Russo et al (Kidney Int (2007) 71, 504–513) gives values 50-times higher. This demonstrated that relatively large quantities of albumin...

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Veröffentlicht in:	Kidney international 2007-11, Vol.72 (10), p.1195-1197
Hauptverfasser:	Russo, L.M., Sandoval, R.M., Brown, D., Molitoris, B.A., Comper, W.D.
Format:	Artikel
Sprache:	eng
Schlagworte:	albumin retrieval albumin transcytosis Albumins - metabolism Albumins - ultrastructure Albuminuria - metabolism Albuminuria - physiopathology Animals Binding Sites Biological and medical sciences Biological Transport Filtration glomerular charge Glomerular Filtration Rate Kidney - chemistry Kidney - physiology Kidney - physiopathology Kidney Glomerulus - physiology Kidney Tubules - metabolism Kidney Tubules - pathology Kinetics Low Density Lipoprotein Receptor-Related Protein-2 - metabolism Medical sciences Nephrology. Urinary tract diseases Nephrotic Syndrome - metabolism Nephrotic Syndrome - pathology
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