Slow, medium, or fast re-warming following post-traumatic hypothermia therapy? An ultrastructural perspective

It was hypothesized that rapid rather than slow re-warming following traumatic brain injury (TBI) and short-term hypothermia results in secondary, ultrastructural pathology. After stretch injury to the right optic nerve, adult guinea pigs were randomly allocated to one of six experimental groups. Ei...

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Veröffentlicht in:	Journal of neurotrauma 2005-08, Vol.22 (8), p.873-884
Hauptverfasser:	MAXWELL, William L, WATSON, Anna, QUEEN, Ross, CONWAY, Bernard, RUSSELL, David, NEILSON, Matt, GRAHAM, David I
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - pathology Actin Cytoskeleton - ultrastructure Amyloid beta-Protein Precursor - metabolism Animals Axons - pathology Axons - ultrastructure Biological and medical sciences Biomarkers Body Temperature - physiology Brain damage Brain Injuries - pathology Brain Injuries - physiopathology Brain Injuries - therapy Disease Models, Animal Guinea Pigs Head injuries Hypothermia Hypothermia, Induced - methods Immunohistochemistry Injuries of the nervous system and the skull. Diseases due to physical agents Male Medical sciences Microscopy, Electron, Transmission Microtubules - pathology Microtubules - ultrastructure Nerve Degeneration - pathology Nerve Degeneration - physiopathology Nerve Degeneration - prevention & control Neurology Optic Nerve - pathology Optic Nerve - physiopathology Optic Nerve - ultrastructure Optic Nerve Injuries - pathology Optic Nerve Injuries - physiopathology Optic Nerve Injuries - therapy Rodents Temperature Time Factors Traumas. Diseases due to physical agents
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