Escheriosome-mediated delivery of recombinant ribosomal L7/L12 protein confers protection against murine brucellosis

Abstract Brucellosis is an important zoonotic disease that causes abortion in cattle and undulant fever, arthritis, endocarditis and meningitis in human. In spite of the fact that immunization could be an efficient measure to control brucellosis, not a single ideal vaccine against this important dis...

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Veröffentlicht in:	Vaccine 2007-11, Vol.25 (46), p.7873-7884
Hauptverfasser:	Mallick, A.I, Singha, H, Khan, S, Anwar, T, Ansari, M.A, Khalid, R, Chaudhuri, P, Owais, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion, Septic - genetics Abortion, Septic - immunology Abortion, Septic - prevention & control Adjuvants, Immunologic - genetics Adjuvants, Immunologic - pharmacology Allergy and Immunology Animals Antibody isotype Antigens Antigens, Bacterial - genetics Antigens, Bacterial - immunology Antigens, Bacterial - pharmacology Arthritis - genetics Arthritis - immunology Arthritis - prevention & control Bacteriology Biological and medical sciences Brucella abortus Brucella abortus - genetics Brucella abortus - immunology Brucella Vaccine - genetics Brucella Vaccine - immunology Brucella Vaccine - pharmacology Brucellosis Brucellosis - genetics Brucellosis - immunology Brucellosis - prevention & control Cattle Cellular immunity Cloning Deoxyribonucleic acid Disease Models, Animal DNA E coli Endocarditis - genetics Endocarditis - immunology Endocarditis - prevention & control Escherichia coli Escherichia coli - chemistry Escherichia coli - genetics Escherichia coli - immunology Escheriosome Female Fever - genetics Fever - immunology Fever - prevention & control Fundamental and applied biological sciences. Psychology Humans Immune response Immunization Infections Laboratories Liposomes - chemistry Liposomes - immunology Liposomes - pharmacology Mice Mice, Inbred BALB C Microbiology Miscellaneous Pregnancy Proteins Recombinant Proteins - genetics Recombinant Proteins - immunology Recombinant Proteins - pharmacology Ribosomal protein Ribosomal Proteins - genetics Ribosomal Proteins - immunology Ribosomal Proteins - pharmacology T-Lymphocytes - immunology Vaccines Zoonoses
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