Use of alternate coreceptors on primary cells by two HIV-1 isolates

Two HIV-1 isolates (CM4 and CM9) able to use alternate HIV-1 coreceptors on transfected cell lines were tested for their sensitivity to inhibitors of HIV-1 entry on primary cells. CM4 was able to use CCR5 and Bob/GPR15 efficiently in transfected cells. The R5 isolate grew in Δ32/Δ32 CCR5 PBMC in the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2005-08, Vol.339 (1), p.136-144
Hauptverfasser:	Cilliers, Tonie, Willey, Samantha, Sullivan, W. Mathew, Patience, Trudy, Pugach, Pavel, Coetzer, Mia, Papathanasopoulos, Maria, Moore, John P., Trkola, Alexandra, Clapham, Paul, Morris, Lynn
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alternate coreceptors Amino Acid Sequence Bob/GPR15 CCR8 Cell Line Female HIV Envelope Protein gp120 - genetics HIV Infections - virology HIV-1 HIV-1 - genetics HIV-1 - physiology Human immunodeficiency virus 1 Humans Male Molecular Sequence Data Receptors, Chemokine - metabolism Receptors, HIV - metabolism Virus Replication
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!