Influence of Patient Selection on the Outcome of Capsule Endoscopy in Patients With Chronic Gastrointestinal Bleeding
BACKGROUND:In chronic gastrointestinal bleeding, success rates in the range of 48% to 76% have been reported for diagnosing clear bleeding sources using capsule endoscopy. The influence of patient selection on the numbers of positive findings yielded by capsule endoscopy is as yet unclear. METHODS:F...
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| Veröffentlicht in: | Journal of clinical gastroenterology 2005-09, Vol.39 (8), p.684-688 |
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| creator | May, Andrea Wardak, Ahad Nachbar, Lars Remke, Stefanie Ell, Christian |
| description | BACKGROUND:In chronic gastrointestinal bleeding, success rates in the range of 48% to 76% have been reported for diagnosing clear bleeding sources using capsule endoscopy. The influence of patient selection on the numbers of positive findings yielded by capsule endoscopy is as yet unclear.
METHODS:From April 2001 to June 2003, capsule endoscopy was carried out in 74 of a total of 127 patients (58%) who presented for capsule endoscopy with a high suspicion of gastrointestinal bleeding in the small-bowel region. Seventy of the 74 patients were included in the analysis. This group of patients was divided into a study group (32 patients) and a post-study group (38 patients), and the two groups were compared.
RESULTS:Stricter patient selection was carried out in the study group than in the post-study group49% of those in the study group underwent capsule endoscopy, compared with 65% of those in the post-study group. The overall success rate for detecting relevant bleeding sources was 54%; in the study group, the rate was 66%; whereas in the post-study group, it was only 45%. Significant differences observed between the two groups of patients included the lowest hemoglobin value (5.9 ± 1.4 g/dL in the study group, compared with 7.7 ± 2.1 g/dL in the post-study group) and transfusion requirements (a median of 10 units in the study group, vs. 2 units in the post-study group). None of the patients who had a minimum hemoglobin value ≥10 g/dL had a positive capsule result.
CONCLUSIONS:Patient selection has a considerable influence on the success rate of capsule endoscopy. In patients with chronic gastrointestinal bleeding, the minimum hemoglobin value and transfusion requirements appear to be the decisive parameters. |
| doi_str_mv | 10.1097/01.mcg.0000173857.22933.3b |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68451075</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68451075</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3927-2dfbff6245370ea8c73f8f5b7c89a9bcc654b4fcb011c93f7bdc67c3688d964b3</originalsourceid><addsrcrecordid>eNpFkW2LFSEYhiWK9rT1F0KC-jaTLzOj9q09bNvCwgYVfRR1dMdy9KQOy_775rzEEUF8uB7vh0sA3mHUYiTYR4Tb2Ty0aF2YUd6zlhBBaUv1M7DBPRUNQRQ_BxuEBWkQE-gCvCrl9wGn-CW4wAPihDC2ActtdGGx0ViYHPymqrexwu82WFN9inDddbLwfqkmzQdmq3ZlCRZexzEVk3ZP0Mf_jQX-8nWC2ymn6A28UaXm5GO1pfqoArwK1o4-PrwGL5wKxb45nZfg55frH9uvzd39ze32811jqCCsIaPTzg2k6ylDVnHDqOOu18xwoYQ2Zug73TmjEcZGUMf0aAZm6MD5KIZO00vw4fjuLqe_yzqFnH0xNgQVbVqKHHjXY8T6Ffx0BE1OpWTr5C77WeUniZHcS5cIy1W6PEuXB-mS7lPenlIWPdvx3HqyvALvT4AqRgWXVTS-nDmGGCcDX7nuyD2mUG0uf8LyaLOcrAp1OkR3nA7r76IeifXW7EuM_gP3FZ0i</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68451075</pqid></control><display><type>article</type><title>Influence of Patient Selection on the Outcome of Capsule Endoscopy in Patients With Chronic Gastrointestinal Bleeding</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>May, Andrea ; Wardak, Ahad ; Nachbar, Lars ; Remke, Stefanie ; Ell, Christian</creator><creatorcontrib>May, Andrea ; Wardak, Ahad ; Nachbar, Lars ; Remke, Stefanie ; Ell, Christian</creatorcontrib><description>BACKGROUND:In chronic gastrointestinal bleeding, success rates in the range of 48% to 76% have been reported for diagnosing clear bleeding sources using capsule endoscopy. The influence of patient selection on the numbers of positive findings yielded by capsule endoscopy is as yet unclear.
METHODS:From April 2001 to June 2003, capsule endoscopy was carried out in 74 of a total of 127 patients (58%) who presented for capsule endoscopy with a high suspicion of gastrointestinal bleeding in the small-bowel region. Seventy of the 74 patients were included in the analysis. This group of patients was divided into a study group (32 patients) and a post-study group (38 patients), and the two groups were compared.
RESULTS:Stricter patient selection was carried out in the study group than in the post-study group49% of those in the study group underwent capsule endoscopy, compared with 65% of those in the post-study group. The overall success rate for detecting relevant bleeding sources was 54%; in the study group, the rate was 66%; whereas in the post-study group, it was only 45%. Significant differences observed between the two groups of patients included the lowest hemoglobin value (5.9 ± 1.4 g/dL in the study group, compared with 7.7 ± 2.1 g/dL in the post-study group) and transfusion requirements (a median of 10 units in the study group, vs. 2 units in the post-study group). None of the patients who had a minimum hemoglobin value ≥10 g/dL had a positive capsule result.
CONCLUSIONS:Patient selection has a considerable influence on the success rate of capsule endoscopy. In patients with chronic gastrointestinal bleeding, the minimum hemoglobin value and transfusion requirements appear to be the decisive parameters.</description><identifier>ISSN: 0192-0790</identifier><identifier>EISSN: 1539-2031</identifier><identifier>DOI: 10.1097/01.mcg.0000173857.22933.3b</identifier><identifier>PMID: 16082277</identifier><identifier>CODEN: JCGADC</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins, Inc</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anemias. Hemoglobinopathies ; Biological and medical sciences ; Chronic Disease ; Diagnosis, Differential ; Digestive system. Abdomen ; Diseases of red blood cells ; Endoscopy ; Endoscopy, Gastrointestinal - methods ; Female ; Follow-Up Studies ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastrointestinal Hemorrhage - diagnosis ; Hematologic and hematopoietic diseases ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Male ; Medical sciences ; Middle Aged ; Other diseases. Semiology ; Outcome Assessment (Health Care) ; Patient Selection ; Reproducibility of Results ; Retrospective Studies ; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus ; Telemetry - instrumentation</subject><ispartof>Journal of clinical gastroenterology, 2005-09, Vol.39 (8), p.684-688</ispartof><rights>2005 Lippincott Williams & Wilkins, Inc.</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3927-2dfbff6245370ea8c73f8f5b7c89a9bcc654b4fcb011c93f7bdc67c3688d964b3</citedby><cites>FETCH-LOGICAL-c3927-2dfbff6245370ea8c73f8f5b7c89a9bcc654b4fcb011c93f7bdc67c3688d964b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27931,27932</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17078268$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16082277$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>May, Andrea</creatorcontrib><creatorcontrib>Wardak, Ahad</creatorcontrib><creatorcontrib>Nachbar, Lars</creatorcontrib><creatorcontrib>Remke, Stefanie</creatorcontrib><creatorcontrib>Ell, Christian</creatorcontrib><title>Influence of Patient Selection on the Outcome of Capsule Endoscopy in Patients With Chronic Gastrointestinal Bleeding</title><title>Journal of clinical gastroenterology</title><addtitle>J Clin Gastroenterol</addtitle><description>BACKGROUND:In chronic gastrointestinal bleeding, success rates in the range of 48% to 76% have been reported for diagnosing clear bleeding sources using capsule endoscopy. The influence of patient selection on the numbers of positive findings yielded by capsule endoscopy is as yet unclear.
METHODS:From April 2001 to June 2003, capsule endoscopy was carried out in 74 of a total of 127 patients (58%) who presented for capsule endoscopy with a high suspicion of gastrointestinal bleeding in the small-bowel region. Seventy of the 74 patients were included in the analysis. This group of patients was divided into a study group (32 patients) and a post-study group (38 patients), and the two groups were compared.
RESULTS:Stricter patient selection was carried out in the study group than in the post-study group49% of those in the study group underwent capsule endoscopy, compared with 65% of those in the post-study group. The overall success rate for detecting relevant bleeding sources was 54%; in the study group, the rate was 66%; whereas in the post-study group, it was only 45%. Significant differences observed between the two groups of patients included the lowest hemoglobin value (5.9 ± 1.4 g/dL in the study group, compared with 7.7 ± 2.1 g/dL in the post-study group) and transfusion requirements (a median of 10 units in the study group, vs. 2 units in the post-study group). None of the patients who had a minimum hemoglobin value ≥10 g/dL had a positive capsule result.
CONCLUSIONS:Patient selection has a considerable influence on the success rate of capsule endoscopy. In patients with chronic gastrointestinal bleeding, the minimum hemoglobin value and transfusion requirements appear to be the decisive parameters.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anemias. Hemoglobinopathies</subject><subject>Biological and medical sciences</subject><subject>Chronic Disease</subject><subject>Diagnosis, Differential</subject><subject>Digestive system. Abdomen</subject><subject>Diseases of red blood cells</subject><subject>Endoscopy</subject><subject>Endoscopy, Gastrointestinal - methods</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastrointestinal Hemorrhage - diagnosis</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Other diseases. Semiology</subject><subject>Outcome Assessment (Health Care)</subject><subject>Patient Selection</subject><subject>Reproducibility of Results</subject><subject>Retrospective Studies</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><subject>Telemetry - instrumentation</subject><issn>0192-0790</issn><issn>1539-2031</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkW2LFSEYhiWK9rT1F0KC-jaTLzOj9q09bNvCwgYVfRR1dMdy9KQOy_775rzEEUF8uB7vh0sA3mHUYiTYR4Tb2Ty0aF2YUd6zlhBBaUv1M7DBPRUNQRQ_BxuEBWkQE-gCvCrl9wGn-CW4wAPihDC2ActtdGGx0ViYHPymqrexwu82WFN9inDddbLwfqkmzQdmq3ZlCRZexzEVk3ZP0Mf_jQX-8nWC2ymn6A28UaXm5GO1pfqoArwK1o4-PrwGL5wKxb45nZfg55frH9uvzd39ze32811jqCCsIaPTzg2k6ylDVnHDqOOu18xwoYQ2Zug73TmjEcZGUMf0aAZm6MD5KIZO00vw4fjuLqe_yzqFnH0xNgQVbVqKHHjXY8T6Ffx0BE1OpWTr5C77WeUniZHcS5cIy1W6PEuXB-mS7lPenlIWPdvx3HqyvALvT4AqRgWXVTS-nDmGGCcDX7nuyD2mUG0uf8LyaLOcrAp1OkR3nA7r76IeifXW7EuM_gP3FZ0i</recordid><startdate>200509</startdate><enddate>200509</enddate><creator>May, Andrea</creator><creator>Wardak, Ahad</creator><creator>Nachbar, Lars</creator><creator>Remke, Stefanie</creator><creator>Ell, Christian</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>200509</creationdate><title>Influence of Patient Selection on the Outcome of Capsule Endoscopy in Patients With Chronic Gastrointestinal Bleeding</title><author>May, Andrea ; Wardak, Ahad ; Nachbar, Lars ; Remke, Stefanie ; Ell, Christian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3927-2dfbff6245370ea8c73f8f5b7c89a9bcc654b4fcb011c93f7bdc67c3688d964b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anemias. Hemoglobinopathies</topic><topic>Biological and medical sciences</topic><topic>Chronic Disease</topic><topic>Diagnosis, Differential</topic><topic>Digestive system. Abdomen</topic><topic>Diseases of red blood cells</topic><topic>Endoscopy</topic><topic>Endoscopy, Gastrointestinal - methods</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Gastrointestinal Hemorrhage - diagnosis</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Other diseases. Semiology</topic><topic>Outcome Assessment (Health Care)</topic><topic>Patient Selection</topic><topic>Reproducibility of Results</topic><topic>Retrospective Studies</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><topic>Telemetry - instrumentation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>May, Andrea</creatorcontrib><creatorcontrib>Wardak, Ahad</creatorcontrib><creatorcontrib>Nachbar, Lars</creatorcontrib><creatorcontrib>Remke, Stefanie</creatorcontrib><creatorcontrib>Ell, Christian</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Journal of clinical gastroenterology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>May, Andrea</au><au>Wardak, Ahad</au><au>Nachbar, Lars</au><au>Remke, Stefanie</au><au>Ell, Christian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of Patient Selection on the Outcome of Capsule Endoscopy in Patients With Chronic Gastrointestinal Bleeding</atitle><jtitle>Journal of clinical gastroenterology</jtitle><addtitle>J Clin Gastroenterol</addtitle><date>2005-09</date><risdate>2005</risdate><volume>39</volume><issue>8</issue><spage>684</spage><epage>688</epage><pages>684-688</pages><issn>0192-0790</issn><eissn>1539-2031</eissn><coden>JCGADC</coden><abstract>BACKGROUND:In chronic gastrointestinal bleeding, success rates in the range of 48% to 76% have been reported for diagnosing clear bleeding sources using capsule endoscopy. The influence of patient selection on the numbers of positive findings yielded by capsule endoscopy is as yet unclear.
METHODS:From April 2001 to June 2003, capsule endoscopy was carried out in 74 of a total of 127 patients (58%) who presented for capsule endoscopy with a high suspicion of gastrointestinal bleeding in the small-bowel region. Seventy of the 74 patients were included in the analysis. This group of patients was divided into a study group (32 patients) and a post-study group (38 patients), and the two groups were compared.
RESULTS:Stricter patient selection was carried out in the study group than in the post-study group49% of those in the study group underwent capsule endoscopy, compared with 65% of those in the post-study group. The overall success rate for detecting relevant bleeding sources was 54%; in the study group, the rate was 66%; whereas in the post-study group, it was only 45%. Significant differences observed between the two groups of patients included the lowest hemoglobin value (5.9 ± 1.4 g/dL in the study group, compared with 7.7 ± 2.1 g/dL in the post-study group) and transfusion requirements (a median of 10 units in the study group, vs. 2 units in the post-study group). None of the patients who had a minimum hemoglobin value ≥10 g/dL had a positive capsule result.
CONCLUSIONS:Patient selection has a considerable influence on the success rate of capsule endoscopy. In patients with chronic gastrointestinal bleeding, the minimum hemoglobin value and transfusion requirements appear to be the decisive parameters.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>16082277</pmid><doi>10.1097/01.mcg.0000173857.22933.3b</doi><tpages>5</tpages></addata></record> |
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| subjects | Adolescent Adult Aged Aged, 80 and over Anemias. Hemoglobinopathies Biological and medical sciences Chronic Disease Diagnosis, Differential Digestive system. Abdomen Diseases of red blood cells Endoscopy Endoscopy, Gastrointestinal - methods Female Follow-Up Studies Gastroenterology. Liver. Pancreas. Abdomen Gastrointestinal Hemorrhage - diagnosis Hematologic and hematopoietic diseases Humans Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Other diseases. Semiology Outcome Assessment (Health Care) Patient Selection Reproducibility of Results Retrospective Studies Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Telemetry - instrumentation |
| title | Influence of Patient Selection on the Outcome of Capsule Endoscopy in Patients With Chronic Gastrointestinal Bleeding |
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