Predicting ongoing adherence to disease modifying therapies in multiple sclerosis: utility of the health beliefs model
Objective To evaluate ongoing adherence to disease modifying therapies (DMT) among individuals with multiple sclerosis and test the utility of the Health Beliefs Model (HBM) to predict adherence. Design Telephone survey completed at baseline with monthly telephone follow-up for 6 months. Setting Vet...
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| Veröffentlicht in: | Multiple sclerosis 2007-11, Vol.13 (9), p.1146-1152 |
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| container_title | Multiple sclerosis |
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| creator | Turner, A.P. Kivlahan, D.R. Sloan, A.P. Haselkorn, J.K. |
| description | Objective
To evaluate ongoing adherence to disease modifying therapies (DMT) among individuals with multiple sclerosis and test the utility of the Health Beliefs Model (HBM) to predict adherence.
Design
Telephone survey completed at baseline with monthly telephone follow-up for 6 months.
Setting
Veterans Health Administration.
Participants
Eighty-nine veterans with MS actively enrolled in a regional VA MS outpatient clinic currently prescribed DMT.
Measures
Demographic information. Selected items from the Adherence Determinants Questionnaire (ADQ) and Barriers to Care Scale (BACS).
Results
Adherence in this population of ongoing DMT users was relatively high (over 80% achieved 80% adherence at follow-up time points). Logistic regression and hierarchical multiple regression analyses controlling for demographics and disease duration were employed to examine the relationship of HBM constructs of perceived susceptibility, severity, benefits, and barriers to DMT adherence and satisfaction at 2-, 4- and 6-month follow-up. Of the four HBM constructs, only perceived benefits uniquely predicted both outcomes across multiple time points.
Conclusion
Sustained adherence to DMT remains a challenge for an important minority of individuals with MS. The Health Beliefs Model provides insight into psychosocial mechanisms that maintain adherence behavior. In particular, focus upon the perceived benefits of ongoing DMT therapy may be a promising focus for future interventions. Multiple Sclerosis 2007; 13: 1146—1152. http://msj.sagepub.com |
| doi_str_mv | 10.1177/1352458507078911 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68450572</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_1352458507078911</sage_id><sourcerecordid>68450572</sourcerecordid><originalsourceid>FETCH-LOGICAL-c392t-12741fc41123adf1bf416aa1fe5debccbbc006272a23bad1c7c3c493ac399fcd3</originalsourceid><addsrcrecordid>eNp1kc1r3DAQxUVpaNK0956KKKQ3txpJXtm9hdAvCKSH9mxkabSrIFtbSS7sfx-ZXVgI9DSC93tPMzxC3gH7BKDUZxAtl23XMsVU1wO8IFcglWpYr9jL-q5ys-qX5HXOj4wxpUT7ilyC6jeqk_yK_PuV0HpT_Lylcd7GdWq7w4SzQVoitT6jzkinaL07rHKpqt57zNTPdFpC8fuANJuAKWafv9Cl-ODLgUa3snSHOpQdHTF4dHkNwvCGXDgdMr49zWvy59vX33c_mvuH7z_vbu8bI3peGuBKgjMSgAttHYxOwkZrcNhaHI0ZR8PYhiuuuRi1BaOMMLIXutp7Z6y4Jh-PufsU_y6YyzD5bDAEPWNc8rDpZMtaxSv44Rn4GJc0190GDl0nBTCoEDtCpl6aE7phn_yk02EANqyFDM8LqZb3p9xlnNCeDacGKnBzAnQ2OrikZ-PzmeuFamullWuOXNZbPC_334-fAM7Nods</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>218843101</pqid></control><display><type>article</type><title>Predicting ongoing adherence to disease modifying therapies in multiple sclerosis: utility of the health beliefs model</title><source>Access via SAGE</source><source>MEDLINE</source><creator>Turner, A.P. ; Kivlahan, D.R. ; Sloan, A.P. ; Haselkorn, J.K.</creator><creatorcontrib>Turner, A.P. ; Kivlahan, D.R. ; Sloan, A.P. ; Haselkorn, J.K.</creatorcontrib><description>Objective
To evaluate ongoing adherence to disease modifying therapies (DMT) among individuals with multiple sclerosis and test the utility of the Health Beliefs Model (HBM) to predict adherence.
Design
Telephone survey completed at baseline with monthly telephone follow-up for 6 months.
Setting
Veterans Health Administration.
Participants
Eighty-nine veterans with MS actively enrolled in a regional VA MS outpatient clinic currently prescribed DMT.
Measures
Demographic information. Selected items from the Adherence Determinants Questionnaire (ADQ) and Barriers to Care Scale (BACS).
Results
Adherence in this population of ongoing DMT users was relatively high (over 80% achieved 80% adherence at follow-up time points). Logistic regression and hierarchical multiple regression analyses controlling for demographics and disease duration were employed to examine the relationship of HBM constructs of perceived susceptibility, severity, benefits, and barriers to DMT adherence and satisfaction at 2-, 4- and 6-month follow-up. Of the four HBM constructs, only perceived benefits uniquely predicted both outcomes across multiple time points.
Conclusion
Sustained adherence to DMT remains a challenge for an important minority of individuals with MS. The Health Beliefs Model provides insight into psychosocial mechanisms that maintain adherence behavior. In particular, focus upon the perceived benefits of ongoing DMT therapy may be a promising focus for future interventions. Multiple Sclerosis 2007; 13: 1146—1152. http://msj.sagepub.com</description><identifier>ISSN: 1352-4585</identifier><identifier>EISSN: 1477-0970</identifier><identifier>DOI: 10.1177/1352458507078911</identifier><identifier>PMID: 17967842</identifier><identifier>CODEN: MUSCFZ</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Data Collection ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; Female ; Follow-Up Studies ; Health Behavior ; Humans ; Logistic Models ; Male ; Medical sciences ; Middle Aged ; Models, Psychological ; Motivation ; Multiple Sclerosis - psychology ; Multiple Sclerosis - therapy ; Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis ; Neurology ; Outpatients - psychology ; Patient Compliance ; Patient Satisfaction ; Predictive Value of Tests ; Self Efficacy ; Surveys and Questionnaires ; United States ; United States Department of Veterans Affairs</subject><ispartof>Multiple sclerosis, 2007-11, Vol.13 (9), p.1146-1152</ispartof><rights>2008 INIST-CNRS</rights><rights>SAGE Publications © Nov 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c392t-12741fc41123adf1bf416aa1fe5debccbbc006272a23bad1c7c3c493ac399fcd3</citedby><cites>FETCH-LOGICAL-c392t-12741fc41123adf1bf416aa1fe5debccbbc006272a23bad1c7c3c493ac399fcd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/1352458507078911$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/1352458507078911$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19375477$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17967842$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Turner, A.P.</creatorcontrib><creatorcontrib>Kivlahan, D.R.</creatorcontrib><creatorcontrib>Sloan, A.P.</creatorcontrib><creatorcontrib>Haselkorn, J.K.</creatorcontrib><title>Predicting ongoing adherence to disease modifying therapies in multiple sclerosis: utility of the health beliefs model</title><title>Multiple sclerosis</title><addtitle>Mult Scler</addtitle><description>Objective
To evaluate ongoing adherence to disease modifying therapies (DMT) among individuals with multiple sclerosis and test the utility of the Health Beliefs Model (HBM) to predict adherence.
Design
Telephone survey completed at baseline with monthly telephone follow-up for 6 months.
Setting
Veterans Health Administration.
Participants
Eighty-nine veterans with MS actively enrolled in a regional VA MS outpatient clinic currently prescribed DMT.
Measures
Demographic information. Selected items from the Adherence Determinants Questionnaire (ADQ) and Barriers to Care Scale (BACS).
Results
Adherence in this population of ongoing DMT users was relatively high (over 80% achieved 80% adherence at follow-up time points). Logistic regression and hierarchical multiple regression analyses controlling for demographics and disease duration were employed to examine the relationship of HBM constructs of perceived susceptibility, severity, benefits, and barriers to DMT adherence and satisfaction at 2-, 4- and 6-month follow-up. Of the four HBM constructs, only perceived benefits uniquely predicted both outcomes across multiple time points.
Conclusion
Sustained adherence to DMT remains a challenge for an important minority of individuals with MS. The Health Beliefs Model provides insight into psychosocial mechanisms that maintain adherence behavior. In particular, focus upon the perceived benefits of ongoing DMT therapy may be a promising focus for future interventions. Multiple Sclerosis 2007; 13: 1146—1152. http://msj.sagepub.com</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Data Collection</subject><subject>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Health Behavior</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Models, Psychological</subject><subject>Motivation</subject><subject>Multiple Sclerosis - psychology</subject><subject>Multiple Sclerosis - therapy</subject><subject>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</subject><subject>Neurology</subject><subject>Outpatients - psychology</subject><subject>Patient Compliance</subject><subject>Patient Satisfaction</subject><subject>Predictive Value of Tests</subject><subject>Self Efficacy</subject><subject>Surveys and Questionnaires</subject><subject>United States</subject><subject>United States Department of Veterans Affairs</subject><issn>1352-4585</issn><issn>1477-0970</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kc1r3DAQxUVpaNK0956KKKQ3txpJXtm9hdAvCKSH9mxkabSrIFtbSS7sfx-ZXVgI9DSC93tPMzxC3gH7BKDUZxAtl23XMsVU1wO8IFcglWpYr9jL-q5ys-qX5HXOj4wxpUT7ilyC6jeqk_yK_PuV0HpT_Lylcd7GdWq7w4SzQVoitT6jzkinaL07rHKpqt57zNTPdFpC8fuANJuAKWafv9Cl-ODLgUa3snSHOpQdHTF4dHkNwvCGXDgdMr49zWvy59vX33c_mvuH7z_vbu8bI3peGuBKgjMSgAttHYxOwkZrcNhaHI0ZR8PYhiuuuRi1BaOMMLIXutp7Z6y4Jh-PufsU_y6YyzD5bDAEPWNc8rDpZMtaxSv44Rn4GJc0190GDl0nBTCoEDtCpl6aE7phn_yk02EANqyFDM8LqZb3p9xlnNCeDacGKnBzAnQ2OrikZ-PzmeuFamullWuOXNZbPC_334-fAM7Nods</recordid><startdate>20071101</startdate><enddate>20071101</enddate><creator>Turner, A.P.</creator><creator>Kivlahan, D.R.</creator><creator>Sloan, A.P.</creator><creator>Haselkorn, J.K.</creator><general>SAGE Publications</general><general>Arnold</general><general>Sage Publications Ltd</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T5</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9-</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20071101</creationdate><title>Predicting ongoing adherence to disease modifying therapies in multiple sclerosis: utility of the health beliefs model</title><author>Turner, A.P. ; Kivlahan, D.R. ; Sloan, A.P. ; Haselkorn, J.K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c392t-12741fc41123adf1bf416aa1fe5debccbbc006272a23bad1c7c3c493ac399fcd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Data Collection</topic><topic>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Health Behavior</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Models, Psychological</topic><topic>Motivation</topic><topic>Multiple Sclerosis - psychology</topic><topic>Multiple Sclerosis - therapy</topic><topic>Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis</topic><topic>Neurology</topic><topic>Outpatients - psychology</topic><topic>Patient Compliance</topic><topic>Patient Satisfaction</topic><topic>Predictive Value of Tests</topic><topic>Self Efficacy</topic><topic>Surveys and Questionnaires</topic><topic>United States</topic><topic>United States Department of Veterans Affairs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Turner, A.P.</creatorcontrib><creatorcontrib>Kivlahan, D.R.</creatorcontrib><creatorcontrib>Sloan, A.P.</creatorcontrib><creatorcontrib>Haselkorn, J.K.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Multiple sclerosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Turner, A.P.</au><au>Kivlahan, D.R.</au><au>Sloan, A.P.</au><au>Haselkorn, J.K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predicting ongoing adherence to disease modifying therapies in multiple sclerosis: utility of the health beliefs model</atitle><jtitle>Multiple sclerosis</jtitle><addtitle>Mult Scler</addtitle><date>2007-11-01</date><risdate>2007</risdate><volume>13</volume><issue>9</issue><spage>1146</spage><epage>1152</epage><pages>1146-1152</pages><issn>1352-4585</issn><eissn>1477-0970</eissn><coden>MUSCFZ</coden><abstract>Objective
To evaluate ongoing adherence to disease modifying therapies (DMT) among individuals with multiple sclerosis and test the utility of the Health Beliefs Model (HBM) to predict adherence.
Design
Telephone survey completed at baseline with monthly telephone follow-up for 6 months.
Setting
Veterans Health Administration.
Participants
Eighty-nine veterans with MS actively enrolled in a regional VA MS outpatient clinic currently prescribed DMT.
Measures
Demographic information. Selected items from the Adherence Determinants Questionnaire (ADQ) and Barriers to Care Scale (BACS).
Results
Adherence in this population of ongoing DMT users was relatively high (over 80% achieved 80% adherence at follow-up time points). Logistic regression and hierarchical multiple regression analyses controlling for demographics and disease duration were employed to examine the relationship of HBM constructs of perceived susceptibility, severity, benefits, and barriers to DMT adherence and satisfaction at 2-, 4- and 6-month follow-up. Of the four HBM constructs, only perceived benefits uniquely predicted both outcomes across multiple time points.
Conclusion
Sustained adherence to DMT remains a challenge for an important minority of individuals with MS. The Health Beliefs Model provides insight into psychosocial mechanisms that maintain adherence behavior. In particular, focus upon the perceived benefits of ongoing DMT therapy may be a promising focus for future interventions. Multiple Sclerosis 2007; 13: 1146—1152. http://msj.sagepub.com</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>17967842</pmid><doi>10.1177/1352458507078911</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1352-4585 |
| ispartof | Multiple sclerosis, 2007-11, Vol.13 (9), p.1146-1152 |
| issn | 1352-4585 1477-0970 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68450572 |
| source | Access via SAGE; MEDLINE |
| subjects | Adult Aged Biological and medical sciences Data Collection Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Follow-Up Studies Health Behavior Humans Logistic Models Male Medical sciences Middle Aged Models, Psychological Motivation Multiple Sclerosis - psychology Multiple Sclerosis - therapy Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Neurology Outpatients - psychology Patient Compliance Patient Satisfaction Predictive Value of Tests Self Efficacy Surveys and Questionnaires United States United States Department of Veterans Affairs |
| title | Predicting ongoing adherence to disease modifying therapies in multiple sclerosis: utility of the health beliefs model |
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