Low-dose oral enoximone enhances the ability to wean patients with ultra-advanced heart failure from intravenous inotropic support: Results of the oral enoximone in intravenous inotrope-dependent subjects trial

Background We determined whether low-dose oral enoximone could wean patients with ultra-advanced heart failure (UA-HF) from intravenous (IV) inotropic support. Chronic parenteral inotropic therapy in UA-HF is costly and requires an indwelling catheter. An effective and safe oral inotrope would have...

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Veröffentlicht in:	The American heart journal 2007-11, Vol.154 (5), p.861-869
Hauptverfasser:	Feldman, Arthur M., MD, PhD, Oren, Ron M., MD, Abraham, William T., MD, Boehmer, John P., MD, Carson, Peter E., MD, Eichhorn, Eric, MD, Gilbert, Edward M., MD, Kao, Andrew, MD, Leier, Carl V., MD, Lowes, Brian D., MD, Mathier, Michael A., MD, McGrew, Frank A., MD, Metra, Marco, MD, Zisman, Lawrence S., MD, Shakar, Simon F., MD, Krueger, Steven K., MD, Robertson, Alastair D., PhD, White, Bill G., PhD, Gerber, Michael J., MD, Wold, Gwyn E., MSPH, Bristow, Michael R., MD, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Biological and medical sciences Cardiology. Vascular system Cardiomyopathy Cardiotonic Agents - administration & dosage Cardiovascular Dose-Response Relationship, Drug Drug Administration Schedule Drug dosages Drug therapy Enoximone - administration & dosage Female Follow-Up Studies Heart Heart failure Heart Failure - drug therapy Heart Failure - mortality Heart Failure - physiopathology Heart failure, cardiogenic pulmonary edema, cardiac enlargement Humans Infusions, Intravenous Male Medical sciences Middle Aged Mortality Myocardial Contraction - drug effects Myocardial Contraction - physiology Retrospective Studies Survival Rate Treatment Outcome United States - epidemiology Ventricular Function, Left - drug effects Ventricular Function, Left - physiology
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