Graft-versus-host-like disease complicating thymoma: Lack of AIRE expression as a cause of non-hereditary autoimmunity?

Abstract Three patients with graft-versus-host-like enterocolonopathy are reported. Their history was remarkable for thymoma and other autoimmune manifestations such as thrombocytopenia, red cell aplasia, interface dermatitis, Sjogren sialadenits, vanishing bile ducts and rheumatoid arthritis. In al...

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Veröffentlicht in:	Immunology letters 2007-11, Vol.114 (1), p.31-37
Hauptverfasser:	Offerhaus, G. Johan, Schipper, Marguerite E.I, Lazenby, Audrey J, Montgomery, Elizabeth, Morsink, Folkert H.M, Bende, Richard J, Musler, Alex R, van Lier, Rene A.W, van Noesel, Carel J.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIRE AIRE Protein Allergy and Immunology Autoimmunity Colitis - immunology Female Forkhead Transcription Factors - metabolism FOXP3 Graft vs Host Disease - immunology Graft-versus-host-disease Humans Male Microsatellite Middle Aged Mucous Membrane - cytology Mucous Membrane - immunology Mucous Membrane - metabolism T-cell development T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism Thymoma Thymoma - immunology Thymoma - metabolism Thymus Gland - immunology Thymus Gland - metabolism Thymus Neoplasms - immunology Thymus Neoplasms - metabolism Transcription Factors - metabolism
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