Activated microglia cells express argininosuccinate synthetase and argininosuccinate lyase in the rat brain after transient ischemia

Argininosuccinate-synthetase (ASS), argininosuccinate-lyase (ASL) and nitric oxide synthase (NOS) act in the l-arginine-NO- l-citrulline cycle. In the rat brain, ASS is expressed in neurons, ASL in neurons and astroglia in the striatum, both are co-expressed with nNOS in medium-sized neurons. Microg...

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Veröffentlicht in:	Experimental neurology 2007-11, Vol.208 (1), p.100-109
Hauptverfasser:	Bizzoco, Elisa, Faussone-Pellegrini, Maria Simonetta, Vannucchi, Maria Giuliana
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Argininosuccinate Lyase - analysis Argininosuccinate Lyase - metabolism Argininosuccinate lyase, ASL Argininosuccinate Synthase - analysis Argininosuccinate Synthase - metabolism Argininosuccinate synthetase, ASS Biological and medical sciences Brain - enzymology Cerebral Infarction - etiology Cerebral Infarction - pathology Corpus striatum Corpus Striatum - chemistry Corpus Striatum - pathology Focal transient ischemia Frontal Lobe - chemistry Frontal Lobe - pathology Fronto-parietal cortex Inducible nitric oxide synthase, iNOS Ischemic Attack, Transient - complications Ischemic Attack, Transient - enzymology Ischemic Attack, Transient - pathology Ischemic Attack, Transient - physiopathology l-arginine-NO- l-citrulline cycle Male Medical sciences Microglia - chemistry Microglia - enzymology Microglia - pathology Microglia cells Neurologic Examination Neurology Neuronal cells Neurons - chemistry Neurons - pathology Nitric Oxide Synthase Type I - analysis Parietal Lobe - chemistry Parietal Lobe - pathology Rats Rats, Wistar Vascular diseases and vascular malformations of the nervous system
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