Prevention of Diabetes Development in Those with the Metabolic Syndrome

Prevention of Diabetes Development in Those with the Metabolic Syndrome

Metabolic syndrome is characterized by abnormal glucose levels, central obesity, hypertension, elevated triglycerides, and low HDL cholesterol. This article reviews available data regarding the impact of lifestyle modification and drug therapies on the progression to diabetes in high risk individual...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The Medical clinics of North America 2007-11, Vol.91 (6), p.1091-1105
Hauptverfasser: Tupper, Traci, MD, Gopalakrishnan, Geetha, MD
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Obesity Agents - therapeutic use
Diabetes Mellitus - etiology
Diabetes Mellitus - prevention & control
Exercise Therapy - methods
Humans
Internal Medicine
Life Style
Metabolic Syndrome - complications
Prognosis
Weight Loss
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1105
container_issue 6
container_start_page 1091
container_title The Medical clinics of North America
container_volume 91
creator Tupper, Traci, MD
Gopalakrishnan, Geetha, MD
description Metabolic syndrome is characterized by abnormal glucose levels, central obesity, hypertension, elevated triglycerides, and low HDL cholesterol. This article reviews available data regarding the impact of lifestyle modification and drug therapies on the progression to diabetes in high risk individuals, such as those with hypertension, dyslipidemia, obesity, and prediabetes. Lifestyle and pharmacological interventions may alter metabolic parameters and impact progression to diabetes. However, the cost-effectiveness of these interventions are unclear.
doi_str_mv 10.1016/j.mcna.2007.06.006
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68440927</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S002571250700079X</els_id><sourcerecordid>68440927</sourcerecordid><originalsourceid>FETCH-LOGICAL-c409t-71bbad2717bf650d9eb00eec2c5da16dff41827a7344a38c7294c067bbc2f7cc3</originalsourceid><addsrcrecordid>eNp9kcFq3DAURUVoSaZpfyCL4FV34z5pbGkMoVCStAmktJAUuhPS8zOjiS1NJU_K_E2-pV9WmRkIdNHVA717r6RzGTvjUHLg8sO6HNCbUgCoEmQJII_YjNe1mjfLunnFZgCinisu6hP2JqU1AK-FlMfshKtGVg3nM3bzPdIT-dEFX4SuuHLG0kipuMqnfdgMeVU4_-f5YRUSFb_duCrGFRVfaTQ29A6L-51vYxjoLXvdmT7Ru8M8ZT8-Xz9c3szvvn25vfx0N8cKmjG_xlrTCsWV7WQNbUMWgAgF1q3hsu26ii-FMmpRVWaxRCWaCkEqa1F0CnFxyt7vczcx_NpSGvXgElLfG09hm7RcVvkiobJQ7IUYQ0qROr2JbjBxpznoiZ9e64mfnvhpkDrzy6bzQ_rWDtS-WA7AsuBiL6D8xydHUSd05JFaFwlH3Qb3__yP_9ixd96h6R9pR2kdttFneprrJDTo-6nBqUBQkFOan4u_Zb2XdA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68440927</pqid></control><display><type>article</type><title>Prevention of Diabetes Development in Those with the Metabolic Syndrome</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Tupper, Traci, MD ; Gopalakrishnan, Geetha, MD</creator><creatorcontrib>Tupper, Traci, MD ; Gopalakrishnan, Geetha, MD</creatorcontrib><description>Metabolic syndrome is characterized by abnormal glucose levels, central obesity, hypertension, elevated triglycerides, and low HDL cholesterol. This article reviews available data regarding the impact of lifestyle modification and drug therapies on the progression to diabetes in high risk individuals, such as those with hypertension, dyslipidemia, obesity, and prediabetes. Lifestyle and pharmacological interventions may alter metabolic parameters and impact progression to diabetes. However, the cost-effectiveness of these interventions are unclear.</description><identifier>ISSN: 0025-7125</identifier><identifier>EISSN: 1557-9859</identifier><identifier>DOI: 10.1016/j.mcna.2007.06.006</identifier><identifier>PMID: 17964911</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Anti-Obesity Agents - therapeutic use ; Diabetes Mellitus - etiology ; Diabetes Mellitus - prevention &amp; control ; Exercise Therapy - methods ; Humans ; Internal Medicine ; Life Style ; Metabolic Syndrome - complications ; Prognosis ; Weight Loss</subject><ispartof>The Medical clinics of North America, 2007-11, Vol.91 (6), p.1091-1105</ispartof><rights>Elsevier Inc.</rights><rights>2007 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c409t-71bbad2717bf650d9eb00eec2c5da16dff41827a7344a38c7294c067bbc2f7cc3</citedby><cites>FETCH-LOGICAL-c409t-71bbad2717bf650d9eb00eec2c5da16dff41827a7344a38c7294c067bbc2f7cc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.mcna.2007.06.006$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17964911$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tupper, Traci, MD</creatorcontrib><creatorcontrib>Gopalakrishnan, Geetha, MD</creatorcontrib><title>Prevention of Diabetes Development in Those with the Metabolic Syndrome</title><title>The Medical clinics of North America</title><addtitle>Med Clin North Am</addtitle><description>Metabolic syndrome is characterized by abnormal glucose levels, central obesity, hypertension, elevated triglycerides, and low HDL cholesterol. This article reviews available data regarding the impact of lifestyle modification and drug therapies on the progression to diabetes in high risk individuals, such as those with hypertension, dyslipidemia, obesity, and prediabetes. Lifestyle and pharmacological interventions may alter metabolic parameters and impact progression to diabetes. However, the cost-effectiveness of these interventions are unclear.</description><subject>Anti-Obesity Agents - therapeutic use</subject><subject>Diabetes Mellitus - etiology</subject><subject>Diabetes Mellitus - prevention &amp; control</subject><subject>Exercise Therapy - methods</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Life Style</subject><subject>Metabolic Syndrome - complications</subject><subject>Prognosis</subject><subject>Weight Loss</subject><issn>0025-7125</issn><issn>1557-9859</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kcFq3DAURUVoSaZpfyCL4FV34z5pbGkMoVCStAmktJAUuhPS8zOjiS1NJU_K_E2-pV9WmRkIdNHVA717r6RzGTvjUHLg8sO6HNCbUgCoEmQJII_YjNe1mjfLunnFZgCinisu6hP2JqU1AK-FlMfshKtGVg3nM3bzPdIT-dEFX4SuuHLG0kipuMqnfdgMeVU4_-f5YRUSFb_duCrGFRVfaTQ29A6L-51vYxjoLXvdmT7Ru8M8ZT8-Xz9c3szvvn25vfx0N8cKmjG_xlrTCsWV7WQNbUMWgAgF1q3hsu26ii-FMmpRVWaxRCWaCkEqa1F0CnFxyt7vczcx_NpSGvXgElLfG09hm7RcVvkiobJQ7IUYQ0qROr2JbjBxpznoiZ9e64mfnvhpkDrzy6bzQ_rWDtS-WA7AsuBiL6D8xydHUSd05JFaFwlH3Qb3__yP_9ixd96h6R9pR2kdttFneprrJDTo-6nBqUBQkFOan4u_Zb2XdA</recordid><startdate>20071101</startdate><enddate>20071101</enddate><creator>Tupper, Traci, MD</creator><creator>Gopalakrishnan, Geetha, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20071101</creationdate><title>Prevention of Diabetes Development in Those with the Metabolic Syndrome</title><author>Tupper, Traci, MD ; Gopalakrishnan, Geetha, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c409t-71bbad2717bf650d9eb00eec2c5da16dff41827a7344a38c7294c067bbc2f7cc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Anti-Obesity Agents - therapeutic use</topic><topic>Diabetes Mellitus - etiology</topic><topic>Diabetes Mellitus - prevention &amp; control</topic><topic>Exercise Therapy - methods</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Life Style</topic><topic>Metabolic Syndrome - complications</topic><topic>Prognosis</topic><topic>Weight Loss</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tupper, Traci, MD</creatorcontrib><creatorcontrib>Gopalakrishnan, Geetha, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Medical clinics of North America</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tupper, Traci, MD</au><au>Gopalakrishnan, Geetha, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevention of Diabetes Development in Those with the Metabolic Syndrome</atitle><jtitle>The Medical clinics of North America</jtitle><addtitle>Med Clin North Am</addtitle><date>2007-11-01</date><risdate>2007</risdate><volume>91</volume><issue>6</issue><spage>1091</spage><epage>1105</epage><pages>1091-1105</pages><issn>0025-7125</issn><eissn>1557-9859</eissn><abstract>Metabolic syndrome is characterized by abnormal glucose levels, central obesity, hypertension, elevated triglycerides, and low HDL cholesterol. This article reviews available data regarding the impact of lifestyle modification and drug therapies on the progression to diabetes in high risk individuals, such as those with hypertension, dyslipidemia, obesity, and prediabetes. Lifestyle and pharmacological interventions may alter metabolic parameters and impact progression to diabetes. However, the cost-effectiveness of these interventions are unclear.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>17964911</pmid><doi>10.1016/j.mcna.2007.06.006</doi><tpages>15</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0025-7125
ispartof The Medical clinics of North America, 2007-11, Vol.91 (6), p.1091-1105
issn 0025-7125
1557-9859
language eng
recordid cdi_proquest_miscellaneous_68440927
source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Anti-Obesity Agents - therapeutic use
Diabetes Mellitus - etiology
Diabetes Mellitus - prevention & control
Exercise Therapy - methods
Humans
Internal Medicine
Life Style
Metabolic Syndrome - complications
Prognosis
Weight Loss
title Prevention of Diabetes Development in Those with the Metabolic Syndrome
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T21%3A23%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevention%20of%20Diabetes%20Development%20in%C2%A0Those%20with%20the%20Metabolic%20Syndrome&rft.jtitle=The%20Medical%20clinics%20of%20North%20America&rft.au=Tupper,%20Traci,%20MD&rft.date=2007-11-01&rft.volume=91&rft.issue=6&rft.spage=1091&rft.epage=1105&rft.pages=1091-1105&rft.issn=0025-7125&rft.eissn=1557-9859&rft_id=info:doi/10.1016/j.mcna.2007.06.006&rft_dat=%3Cproquest_cross%3E68440927%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68440927&rft_id=info:pmid/17964911&rft_els_id=1_s2_0_S002571250700079X&rfr_iscdi=true