Occurrence of Orally Administered Mulberry 1-Deoxynojirimycin in Rat Plasma

1-Deoxynojirimycin (DNJ), a potent glucosidase inhibitor, is a characteristic constituent of the mulberry leaf. Dietary mulberry DNJ may be beneficial for the suppression of abnormally high blood glucose levels, thereby preventing diabetes mellitus. Although there is considerable interest in the eff...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2007-10, Vol.55 (22), p.8928-8933
Hauptverfasser:	Nakagawa, Kiyotaka, Kubota, Hiroyuki, Kimura, Toshiyuki, Yamashita, Shinji, Tsuzuki, Tsuyoshi, Oikawa, Shinichi, Miyazawa, Teruo
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Deoxynojirimycin 1-Deoxynojirimycin - administration & dosage 1-Deoxynojirimycin - blood 1-Deoxynojirimycin - pharmacokinetics absorption animal models Animals aza sugars Bioactive Constituents bioavailability Biological and medical sciences blood plasma Chromatography Enzyme Inhibitors excretion Food industries Fruit and vegetable industries Fundamental and applied biological sciences. Psychology glucosidases Glucosidases - antagonists & inhibitors HILIC–MS intestinal absorption leaves Male Mass Spectrometry metabolic studies Morus - chemistry mulberries mulberry mulberry 1-deoxynojirimycin oral administration plant extracts Plant Leaves - chemistry rat plasma Rats Rats, Sprague-Dawley
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