Substrate chemistry influences the morphology and biological function of adsorbed extracellular matrix assemblies

In addition to mediating cell signalling events, native extracellular matrix (ECM) assemblies interact with other ECM components, act as reservoirs for soluble signalling molecules and perform structural roles. The potential of native ECM assemblies in the manufacture of biomimetic materials has not...

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Veröffentlicht in:	Biomaterials 2005-12, Vol.26 (34), p.7192-7206
Hauptverfasser:	Sherratt, Michael J., Bax, Daniel V., Chaudhry, Shazia S., Hodson, Nigel, Lu, Jian R., Saravanapavan, Priya, Kielty, Cay M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorption Atomic force microscopy (AFM) Cell Adhesion - drug effects Cell Adhesion - physiology Cell Movement - drug effects Cell Movement - physiology Cell Size - drug effects Cell spreading Cells, Cultured Coated Materials, Biocompatible - chemistry Coated Materials, Biocompatible - pharmacology Collagen Type VI - chemistry Collagen Type VI - pharmacology Extracellular matrix (ECM) Extracellular Matrix Proteins - chemistry Extracellular Matrix Proteins - pharmacology Fibrillins Fibroblasts - cytology Fibroblasts - drug effects Fibroblasts - physiology Humans Materials Testing Microfilament Proteins - chemistry Microfilament Proteins - pharmacology Protein adsorption Protein Binding Surface energy Surface roughness
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