Implantation of preadipocyte-loaded hyaluronic acid-based scaffolds into nude mice to evaluate potential for soft tissue engineering

The reconstruction of soft tissue defects following extensive deep burns or tumor resections remains an unresolved problem in plastic and reconstructive surgery since adequate implant materials are still not available. Preadipocytes, immature precursor cells found between mature adipocytes in adipos...

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Veröffentlicht in:	Biomaterials 2005-12, Vol.26 (34), p.7025-7037
Hauptverfasser:	Hemmrich, Karsten, von Heimburg, Dennis, Rendchen, Raoul, Di Bartolo, Chiara, Milella, Eva, Pallua, Norbert
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - cytology Adipocytes - physiology Adipocytes - transplantation Adipose Tissue - blood supply Adipose Tissue - cytology Adipose Tissue - growth & development Adipose tissue engineering Adolescent Adult Aged Animals Biocompatible Materials - chemistry Cell Culture Techniques - methods Cell Differentiation Cell Proliferation Cells, Cultured Feasibility Studies Guided Tissue Regeneration - instrumentation Guided Tissue Regeneration - methods Humans Hyaluronic acid Hyaluronic Acid - chemistry Implants, Experimental Materials Testing Mice Mice, Nude Middle Aged Neovascularization, Physiologic - physiology Porosity Progenitor cell Tissue Engineering - methods
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