Ligand-Directed Signaling: 50 Ways to Find a Lover

In contrast to earlier concepts, it seems that distinct ligands acting on the same receptor may elicit qualitative different response patterns, a phenomenon given many names, including “functional selectivity,” “agonist-directed trafficking,” “biased agonism,” “protean agonism,” or “ligand-directed...

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Veröffentlicht in:	Molecular pharmacology 2007-11, Vol.72 (5), p.1097-1099
Hauptverfasser:	Michel, Martin C., Alewijnse, Astrid E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-3 Receptor Agonists Adrenergic beta-3 Receptor Antagonists Animals Ligands
Online-Zugang:	Volltext
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