Transfer of antivirals across the human placenta

Viruses cross the placenta and infect the fetus. Antivirals are administered to pregnant women to protect them and the fetus against the viruses. It is necessary to know which antivirals cross the placenta and reach the fetal circulation in pharmacologically significant concentrations in order to pl...

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Veröffentlicht in:	Early human development 2005-08, Vol.81 (8), p.647-654
1. Verfasser:	Pacifici, Gian Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Abacavir Acyclovir Amprenavir Animals Anti-HIV Agents - chemistry Anti-HIV Agents - pharmacokinetics Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Antivirals Biological and medical sciences Care and treatment Diagnosis Didanosine Zalcitabine Embryology: invertebrates and vertebrates. Teratology Female Fundamental and applied biological sciences. Psychology Ganciclovir General aspects. Development. Fetal membranes HIV HIV Infections - drug therapy HIV Infections - metabolism Humans Indinavir Infectious Disease Transmission, Vertical Lamivudine Medical sciences Molecular Weight Nelfinavir Nevirapine Pharmacology. Drug treatments Placenta Placenta - metabolism Placental transfer Pregnancy Pregnancy Complications, Infectious - drug therapy Pregnancy Complications, Infectious - metabolism Pregnant women Ritonavir Saquinavir Stavudine Virus diseases Zidovudine
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