Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine

TRPA1 is a member of the transient receptor potential (TRP) channel family expressed in sensory neurons. The present study focused on the effects of TRPA1 activation on contractile responses in isolated mouse intestine preparations. The jejunum, ileum, and proximal and distal colon were surgically i...

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Veröffentlicht in:	European journal of pharmacology 2007-12, Vol.576 (1), p.143-150
Hauptverfasser:	Penuelas, Angelica, Tashima, Kimihito, Tsuchiya, Shizuko, Matsumoto, Kenjiro, Nakamura, Tomonori, Horie, Syunji, Yano, Shingo
Format:	Artikel
Sprache:	eng
Schlagworte:	Allyl isothiocyanate Animals Biological and medical sciences Capsaicin Capsaicin - pharmacology Colon Contraction Gastrointestinal Motility - drug effects Gastrointestinal Motility - physiology In Vitro Techniques Intestines - drug effects Intestines - physiology Isothiocyanates - pharmacology Male Medical sciences Menthol - pharmacology Mice Pharmacology. Drug treatments Pyrimidinones - pharmacology RNA, Messenger - metabolism Sulfinic Acids - pharmacology Transient Receptor Potential Channels - agonists Transient Receptor Potential Channels - genetics Transient Receptor Potential Channels - physiology TRPA1 TRPA1 Cation Channel TRPM Cation Channels - genetics TRPM Cation Channels - physiology TRPV Cation Channels - genetics TRPV Cation Channels - physiology TRPV1
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