Substance P stimulates late-stage rat osteoblastic bone formation through neurokinin-1 receptors

Abstract Substance P (SP) is a widely distributed neuropeptide that works as a neurotransmitter and neuromodulator. Recently, SP receptors, particularly neurokinin-1 receptors (NK1 -Rs) that have a high affinity for SP, have been observed not only in neuron and immune cells, but also in other periph...

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Veröffentlicht in:	Neuropeptides (Edinburgh) 2007-02, Vol.41 (1), p.25-31
Hauptverfasser:	Goto, T, Nakao, K, Gunjigake, K.K, Kido, M.A, Kobayashi, S, Tanaka, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Biological and medical sciences Bone Development - drug effects Bone Development - physiology Bone formation Cell Differentiation - drug effects Cell Differentiation - physiology Collagen - drug effects Dipeptides - pharmacology DNA Primers Endocrinology & Metabolism Fundamental and applied biological sciences. Psychology Indoles - pharmacology Neurokinin-1 receptor Osteoblastic cell Osteoblasts - drug effects Osteoblasts - physiology Rats Rats, Inbred Strains Receptors, Neurokinin-1 - drug effects Receptors, Neurokinin-1 - physiology RNA, Messenger - genetics Substance P Substance P - analogs & derivatives Substance P - pharmacology Vertebrates: endocrinology
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