Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study

Summary Background Inter-individual differences in biological ageing could affect susceptibility to coronary heart disease. Our aim was to determine whether mean leucocyte telomere length is a predictor of the development of coronary heart disease. Methods We compared telomere lengths at recruitment...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Lancet (British edition) 2007-01, Vol.369 (9556), p.107-114
Hauptverfasser:	Brouilette, Scott W, PhD, Moore, Jasbir S, MSc, McMahon, Alex D, PhD, Thompson, John R, Prof, Ford, Ian, Prof, Shepherd, James, Prof, Packard, Chris J, Prof, Samani, Nilesh J, Prof
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Apoptosis Biological clocks Blood Pressure - drug effects Cardiovascular disease Cardiovascular diseases Case-Control Studies Cell division Cholesterol Cholesterol - blood Coronary Disease - etiology Coronary Disease - prevention & control DNA polymerase Follow-Up Studies Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Informed consent Internal Medicine Leukocytes Male Medical treatment Middle Aged Polymerase Chain Reaction Pravastatin - therapeutic use Prevention Risk Factors Scotland Statins Telomere - drug effects Telomere - genetics Telomere - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!