Primary cutaneous CD30+ anaplastic large-cell lymphomas mimicking keratoacanthomas
Summary Primary cutaneous anaplastic large cell lymphoma (ALCL) may be associated with keratoacanthoma (KA)‐like epithelial hyperplasia and dense eosinophilic and neutrophilic infiltrates. Diagnosis in such cases is challenging both clinically and histologically, because the large atypical lymphoid...
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| Veröffentlicht in: | Clinical and experimental dermatology 2007-11, Vol.32 (6), p.668-671 |
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| container_title | Clinical and experimental dermatology |
| container_volume | 32 |
| creator | Martín, J. M. Ricart, J. M. Monteagudo, C. Alcácer, J. Pinazo, I. Tomás, L. Rausell, N. Jordá, E. |
| description | Summary
Primary cutaneous anaplastic large cell lymphoma (ALCL) may be associated with keratoacanthoma (KA)‐like epithelial hyperplasia and dense eosinophilic and neutrophilic infiltrates. Diagnosis in such cases is challenging both clinically and histologically, because the large atypical lymphoid cells may be obscured by the massive infiltrate of eosinophils and neutrophils, or confused with invasive squamous cell carcinoma or KA. We recently encountered two cases of CD30+ ALCL presenting with a KA‐like tumour on the eyelid and nose, respectively. One showed features of KA histologically, with marked tissue eosinophilia and neutrophilia. |
| doi_str_mv | 10.1111/j.1365-2230.2007.02477.x |
| format | Article |
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Primary cutaneous anaplastic large cell lymphoma (ALCL) may be associated with keratoacanthoma (KA)‐like epithelial hyperplasia and dense eosinophilic and neutrophilic infiltrates. Diagnosis in such cases is challenging both clinically and histologically, because the large atypical lymphoid cells may be obscured by the massive infiltrate of eosinophils and neutrophils, or confused with invasive squamous cell carcinoma or KA. We recently encountered two cases of CD30+ ALCL presenting with a KA‐like tumour on the eyelid and nose, respectively. One showed features of KA histologically, with marked tissue eosinophilia and neutrophilia.</description><identifier>ISSN: 0307-6938</identifier><identifier>EISSN: 1365-2230</identifier><identifier>DOI: 10.1111/j.1365-2230.2007.02477.x</identifier><identifier>PMID: 17953637</identifier><identifier>CODEN: CEDEDE</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Biological and medical sciences ; Dermatology ; Diagnosis, Differential ; Eyelid Neoplasms - diagnosis ; Eyelid Neoplasms - pathology ; Facial Neoplasms - diagnosis ; Facial Neoplasms - pathology ; Female ; Hematologic and hematopoietic diseases ; Humans ; Keratoacanthoma - diagnosis ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Lymphoma, Primary Cutaneous Anaplastic Large Cell - diagnosis ; Lymphoma, Primary Cutaneous Anaplastic Large Cell - pathology ; Male ; Medical sciences ; Middle Aged ; Nose Neoplasms - diagnosis ; Nose Neoplasms - pathology ; Skin Neoplasms - diagnosis ; Skin Neoplasms - pathology ; Tumors of the skin and soft tissue. Premalignant lesions</subject><ispartof>Clinical and experimental dermatology, 2007-11, Vol.32 (6), p.668-671</ispartof><rights>2007 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4667-ef03afa227c1bf7fa28c6b343e7d0ba1ce73cafd5d11619ad3437e76de628bf53</citedby><cites>FETCH-LOGICAL-c4667-ef03afa227c1bf7fa28c6b343e7d0ba1ce73cafd5d11619ad3437e76de628bf53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19202507$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17953637$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Martín, J. M.</creatorcontrib><creatorcontrib>Ricart, J. M.</creatorcontrib><creatorcontrib>Monteagudo, C.</creatorcontrib><creatorcontrib>Alcácer, J.</creatorcontrib><creatorcontrib>Pinazo, I.</creatorcontrib><creatorcontrib>Tomás, L.</creatorcontrib><creatorcontrib>Rausell, N.</creatorcontrib><creatorcontrib>Jordá, E.</creatorcontrib><title>Primary cutaneous CD30+ anaplastic large-cell lymphomas mimicking keratoacanthomas</title><title>Clinical and experimental dermatology</title><addtitle>Clin Exp Dermatol</addtitle><description>Summary
Primary cutaneous anaplastic large cell lymphoma (ALCL) may be associated with keratoacanthoma (KA)‐like epithelial hyperplasia and dense eosinophilic and neutrophilic infiltrates. Diagnosis in such cases is challenging both clinically and histologically, because the large atypical lymphoid cells may be obscured by the massive infiltrate of eosinophils and neutrophils, or confused with invasive squamous cell carcinoma or KA. We recently encountered two cases of CD30+ ALCL presenting with a KA‐like tumour on the eyelid and nose, respectively. One showed features of KA histologically, with marked tissue eosinophilia and neutrophilia.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Diagnosis, Differential</subject><subject>Eyelid Neoplasms - diagnosis</subject><subject>Eyelid Neoplasms - pathology</subject><subject>Facial Neoplasms - diagnosis</subject><subject>Facial Neoplasms - pathology</subject><subject>Female</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Keratoacanthoma - diagnosis</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Lymphoma, Primary Cutaneous Anaplastic Large Cell - diagnosis</subject><subject>Lymphoma, Primary Cutaneous Anaplastic Large Cell - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nose Neoplasms - diagnosis</subject><subject>Nose Neoplasms - pathology</subject><subject>Skin Neoplasms - diagnosis</subject><subject>Skin Neoplasms - pathology</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><issn>0307-6938</issn><issn>1365-2230</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1P3DAQhi1EBVvKX6hygUuV1B-xJzn0UC0UKm1bWlHRmzVxHPBuPhY7q-7-exKygmPri0ea5x2PH0IiRhM2nI_LhAklY84FTTilkFCeAiTbAzJ7aRySGRUUYpWL7Ji8DWFJKRMM5BE5ZpBLoQTMyK8b7xr0u8hsemxttwnR_ELQDxG2uK4x9M5ENfp7Gxtb11G9a9YPXYMhalzjzMq199HKeuw7NNj2z6135E2FdbCn-_uE_P5yeTu_jhc_rr7OPy9ikyoFsa2owAo5B8OKCoYqM6oQqbBQ0gKZsSAMVqUsGVMsx3JogQVVWsWzopLihJxPc9e-e9zY0OvGhXHL6R9aZSkXXKb_BDmV-SBwBLMJNL4LwdtKryc7mlE9itdLPfrVo189itfP4vV2iL7fv7EpGlu-BvemB-BsD2AwWFceW-PCK5dzyiUduU8T99fVdvffC-j55cVYDfl4yrvQ2-1LHv1KKxAg9d33K337bfEzvfkDw7AniWeuPA</recordid><startdate>200711</startdate><enddate>200711</enddate><creator>Martín, J. M.</creator><creator>Ricart, J. M.</creator><creator>Monteagudo, C.</creator><creator>Alcácer, J.</creator><creator>Pinazo, I.</creator><creator>Tomás, L.</creator><creator>Rausell, N.</creator><creator>Jordá, E.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>200711</creationdate><title>Primary cutaneous CD30+ anaplastic large-cell lymphomas mimicking keratoacanthomas</title><author>Martín, J. M. ; Ricart, J. M. ; Monteagudo, C. ; Alcácer, J. ; Pinazo, I. ; Tomás, L. ; Rausell, N. ; Jordá, E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4667-ef03afa227c1bf7fa28c6b343e7d0ba1ce73cafd5d11619ad3437e76de628bf53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Diagnosis, Differential</topic><topic>Eyelid Neoplasms - diagnosis</topic><topic>Eyelid Neoplasms - pathology</topic><topic>Facial Neoplasms - diagnosis</topic><topic>Facial Neoplasms - pathology</topic><topic>Female</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Keratoacanthoma - diagnosis</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Lymphoma, Primary Cutaneous Anaplastic Large Cell - diagnosis</topic><topic>Lymphoma, Primary Cutaneous Anaplastic Large Cell - pathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nose Neoplasms - diagnosis</topic><topic>Nose Neoplasms - pathology</topic><topic>Skin Neoplasms - diagnosis</topic><topic>Skin Neoplasms - pathology</topic><topic>Tumors of the skin and soft tissue. Premalignant lesions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Martín, J. M.</creatorcontrib><creatorcontrib>Ricart, J. M.</creatorcontrib><creatorcontrib>Monteagudo, C.</creatorcontrib><creatorcontrib>Alcácer, J.</creatorcontrib><creatorcontrib>Pinazo, I.</creatorcontrib><creatorcontrib>Tomás, L.</creatorcontrib><creatorcontrib>Rausell, N.</creatorcontrib><creatorcontrib>Jordá, E.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical and experimental dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martín, J. M.</au><au>Ricart, J. M.</au><au>Monteagudo, C.</au><au>Alcácer, J.</au><au>Pinazo, I.</au><au>Tomás, L.</au><au>Rausell, N.</au><au>Jordá, E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary cutaneous CD30+ anaplastic large-cell lymphomas mimicking keratoacanthomas</atitle><jtitle>Clinical and experimental dermatology</jtitle><addtitle>Clin Exp Dermatol</addtitle><date>2007-11</date><risdate>2007</risdate><volume>32</volume><issue>6</issue><spage>668</spage><epage>671</epage><pages>668-671</pages><issn>0307-6938</issn><eissn>1365-2230</eissn><coden>CEDEDE</coden><abstract>Summary
Primary cutaneous anaplastic large cell lymphoma (ALCL) may be associated with keratoacanthoma (KA)‐like epithelial hyperplasia and dense eosinophilic and neutrophilic infiltrates. Diagnosis in such cases is challenging both clinically and histologically, because the large atypical lymphoid cells may be obscured by the massive infiltrate of eosinophils and neutrophils, or confused with invasive squamous cell carcinoma or KA. We recently encountered two cases of CD30+ ALCL presenting with a KA‐like tumour on the eyelid and nose, respectively. One showed features of KA histologically, with marked tissue eosinophilia and neutrophilia.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>17953637</pmid><doi>10.1111/j.1365-2230.2007.02477.x</doi><tpages>4</tpages></addata></record> |
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| subjects | Adult Biological and medical sciences Dermatology Diagnosis, Differential Eyelid Neoplasms - diagnosis Eyelid Neoplasms - pathology Facial Neoplasms - diagnosis Facial Neoplasms - pathology Female Hematologic and hematopoietic diseases Humans Keratoacanthoma - diagnosis Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, Primary Cutaneous Anaplastic Large Cell - diagnosis Lymphoma, Primary Cutaneous Anaplastic Large Cell - pathology Male Medical sciences Middle Aged Nose Neoplasms - diagnosis Nose Neoplasms - pathology Skin Neoplasms - diagnosis Skin Neoplasms - pathology Tumors of the skin and soft tissue. Premalignant lesions |
| title | Primary cutaneous CD30+ anaplastic large-cell lymphomas mimicking keratoacanthomas |
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