The insulin-like growth factor type 1 receptor and colorectal neoplasia: insights into invasion

Summary This study examines the expression of the insulin-like growth factor type 1 receptor (IGF-1R) in colorectal neoplasia. Previous studies have shown that the IGF-1R is expressed at high levels in normal embryonic stem cells and in many cancer phenotypes. However, lower IGF-1R levels are expres...

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Veröffentlicht in:	Human pathology 2007-11, Vol.38 (11), p.1590-1602
Hauptverfasser:	Allison, Andrew S., MD, FRCSEd, McIntyre, Margaret A., FRCPath, McArdle, Colin, MD, FRCS, Habib, Fouad K., PhD, FRSC
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenomatous Polyps - pathology Aged Behavior Biological and medical sciences Blotting, Northern Blotting, Western Cancer Cell adhesion Colorectal neoplasia Colorectal Neoplasms - pathology Colorectal Neoplasms - physiopathology Confidence intervals Epithelial mesenchymal transformation Female Gastroenterology. Liver. Pancreas. Abdomen Gene expression Humans Immunohistochemistry Insulin-like growth factor type 1 receptor Insulin-like growth factors Intestinal Mucosa - physiology Invasion Investigative techniques, diagnostic techniques (general aspects) Kinases Male Medical sciences Neoplasm Invasiveness - physiopathology Pathology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Receptor, IGF Type 1 Stem cells Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Studies Tumors
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