Spectral karyotyping demonstrates genetically unstable skin-homing T lymphocytes in cutaneous T-cell lymphoma

: We initially established cell lines from skin biopsies from four patients (MF8, MF18, MF19 and MF31) in early stages of cutaneous T‐cell lymphoma (CTCL) in 1999. After 3 weeks of culture, skin‐homing T lymphocytes were stimulated with phytohaemagglutinin. Metaphase spreads were analysed using spe...

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Veröffentlicht in:	Experimental dermatology 2007-02, Vol.16 (2), p.98-103
Hauptverfasser:	Padilla-Nash, Hesed M., Wu, Kaida, Just, Helle, Ried, Thomas, Thestrup-Pedersen, Kristian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Cell Transformation, Neoplastic - pathology Cells, Cultured Chromosome Aberrations cutaneous T-cell lymphoma cytogenetic analysis Dermatology Female genomic instability Hematologic and hematopoietic diseases Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, T-Cell, Cutaneous - pathology Male Medical sciences mycosis fungoides Skin Neoplasms - pathology Spectral Karyotyping T-Lymphocytes - pathology
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