Quantitative analysis of somatostatin receptor subtype (SSTR1–5) gene expression levels in somatotropinomas and non-functioning pituitary adenomas

Objective: It is believed that the variable effectiveness of somatostatin analogs in post-surgical management of somatotropinomas and non-functioning pituitary adenomas (NFPA) may be due in part to variable expression of somatostatin receptor isoforms (SSTR1–5), within and between pituitary tumor ty...

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Veröffentlicht in:	European journal of endocrinology 2007-01, Vol.156 (1), p.65-74
Hauptverfasser:	Taboada, Giselle F, Luque, Raul M, Bastos, Wildebranham, Guimarães, Renata F C, Marcondes, Jorge B, Chimelli, Leila M C, Fontes, Rosita, Mata, Paulo J P, Filho, Paulo Niemeyer, Carvalho, Denise P, Kineman, Rhonda D, Gadelha, Mônica R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acromegaly - etiology Adenoma - metabolism Adenoma - surgery Adult Antisense Elements (Genetics) Biological and medical sciences Clinical Studies DNA Primers Endocrinopathies Female Follow-Up Studies Fundamental and applied biological sciences. Psychology Gene Dosage Gene Expression Gene Expression Regulation, Neoplastic - genetics Human Growth Hormone - metabolism Humans Hypothalamus. Hypophysis. Epiphysis (diseases) Male Medical sciences Middle Aged Molecular Sequence Data Non tumoral diseases. Target tissue resistance. Benign neoplasms Octreotide - therapeutic use Pituitary Neoplasms - metabolism Pituitary Neoplasms - surgery Receptors, Somatostatin - genetics Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis Vertebrates: endocrinology
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