Phenotypic heterogeneity is an evolutionarily conserved feature of the endothelium

Mammalian endothelial cells (ECs) display marked phenotypic heterogeneity. Little is known about the evolutionary mechanisms underlying EC heterogeneity. The last common ancestor of hagfish and gnathostomes was also the last common ancestor of all extant vertebrates, which lived some time more than...

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Veröffentlicht in:	Blood 2007-01, Vol.109 (2), p.613-615
Hauptverfasser:	Yano, Kiichiro, Gale, Daniel, Massberg, Steffen, Cheruvu, Pavan K., Monahan-Earley, Rita, Morgan, Ellen S., Haig, David, von Andrian, Ulrich H., Dvorak, Ann M., Aird, William C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - ultrastructure Biological and medical sciences Biological Evolution Blood vessels and receptors Capillaries - cytology Cell Adhesion Dermis - blood supply Dermis - ultrastructure Endothelium - ultrastructure Fundamental and applied biological sciences. Psychology Hagfishes - physiology Heart - anatomy & histology Lectins Leukocytes - cytology Liver - ultrastructure Phenotype Staining and Labeling Venules - cytology Vertebrates: cardiovascular system
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