IL-18 is expressed in the intercalated cell of human kidney

We determined the cellular location of interleukin-18 (IL-18) and caspase-1 and the purinergic receptor P2X7, two proteins necessary for its activation and secretion. The mRNA and protein of IL-18 were detectable in normal human kidney by means of polymerase chain reaction (PCR), in situ hybridizati...

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Veröffentlicht in:	Kidney international 2007-11, Vol.72 (9), p.1081-1087
Hauptverfasser:	Gauer, S., Sichler, O., Obermüller, N., Holzmann, Y., Kiss, E., Sobkowiak, E., Pfeilschifter, J., Geiger, H., Mühl, H., Hauser, I.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aquaporin 2 - metabolism Biological and medical sciences Calbindin 1 Calbindins Caspase 1 - metabolism collecting ducts distal tubule Female Humans immunohistochemistry immunology Interleukin-18 - metabolism Kidney Tubules, Collecting - cytology Kidney Tubules, Collecting - metabolism Kidney Tubules, Distal - cytology Kidney Tubules, Distal - metabolism Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Nephrons - cytology Nephrons - metabolism Receptors, Purinergic P2 - metabolism Receptors, Purinergic P2X7 RNA, Messenger - metabolism S100 Calcium Binding Protein G - metabolism
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