Identification of twinfilin-2 as a factor involved in neurite outgrowth by RNAi-based screen

Using RNA interference (RNAi) to suppress gene expression, we attempted to identify tyrosine kinases involved in the extension of neurites from SH-SY5Y cells. A comprehensive analysis of gene “knock-down” profiles with small interfering RNAs (siRNAs) revealed candidate proteins that might control ne...

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Veröffentlicht in:	Biochemical and biophysical research communications 2007-11, Vol.363 (4), p.926-930
Hauptverfasser:	Yamada, Shigeru, Uchimura, Eiichiro, Ueda, Takanori, Nomura, Takashi, Fujita, Satoshi, Matsumoto, Kayo, Funeriu, Daniel P., Miyake, Masato, Miyake, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin-binding protein Animals Carrier Proteins - genetics Carrier Proteins - metabolism Cell Line, Tumor Gene Expression Regulation Humans Microfilament Proteins Neurite extension Neurites - drug effects Neurites - metabolism Protein-Tyrosine Kinases - genetics Protein-Tyrosine Kinases - metabolism Rats RNA Interference Tretinoin - pharmacology Tyrosine kinase
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