Marburg Hemorrhagic Fever in Durba and Watsa, Democratic Republic of the Congo: Clinical Documentation, Features of Illness, and Treatment
The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initia...
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Veröffentlicht in: | The Journal of infectious diseases 2007-11, Vol.196 (Supplement-2), p.S148-S153 |
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creator | Colebunders, Robert Tshomba, Antoine Van Kerkhove, Maria D. Bausch, Daniel G. Campbell, Pat Libande, Modeste Pirard, Patricia Tshioko, Florimond Mardel, Simon Mulangu, Sabue Sleurs, Hilde Rollin, Pierre E. Muyembe-Tamfum, Jean-Jacques Jeffs, Benjamin Borchert, Matthias |
description | The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initial symptoms included fever, headache, general pain, nausea, vomiting, and anorexia (median day of onset, day 1–2), followed by hemorrhagic manifestations (day 5–8+), and terminal symptoms included confusion, agitation, coma, anuria, and shock. Treatment in isolation wards was acceptable, but the quality of clinical documentation was unsatisfactory. Improved clinical documentation is necessary for a basic evaluation of supportive treatment. |
doi_str_mv | 10.1086/520543 |
format | Article |
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Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initial symptoms included fever, headache, general pain, nausea, vomiting, and anorexia (median day of onset, day 1–2), followed by hemorrhagic manifestations (day 5–8+), and terminal symptoms included confusion, agitation, coma, anuria, and shock. Treatment in isolation wards was acceptable, but the quality of clinical documentation was unsatisfactory. Improved clinical documentation is necessary for a basic evaluation of supportive treatment.</description><identifier>ISSN: 0022-1899</identifier><identifier>EISSN: 1537-6613</identifier><identifier>DOI: 10.1086/520543</identifier><identifier>PMID: 17940943</identifier><identifier>CODEN: JIDIAQ</identifier><language>eng</language><publisher>Chicago, IL: The University of Chicago Press</publisher><subject>Animals ; Biological and medical sciences ; Democratic Republic of the Congo - epidemiology ; Diarrhea ; Disease outbreaks ; Disease Progression ; Documentation ; Epidemiology and Outbreak Management ; Female ; Fever ; Headache ; Human viral diseases ; Humans ; Infectious diseases ; Male ; Marburg disease, ebola disease ; Marburg virus ; Marburg virus disease ; Marburg Virus Disease - epidemiology ; Marburg Virus Disease - mortality ; Marburg Virus Disease - physiopathology ; Marburgvirus ; Medical Records ; Medical sciences ; Pain ; Retrospective Studies ; Survival Rate ; Symptoms ; Tropical medicine ; Tropical viral diseases ; Viral diseases ; Vomiting</subject><ispartof>The Journal of infectious diseases, 2007-11, Vol.196 (Supplement-2), p.S148-S153</ispartof><rights>Copyright 2007 Infectious Diseases Society of America</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-24f6f1d03d7dac13f8b3126a244666f123fb33dc9fbdd42144fb8d94bf134cda3</citedby><cites>FETCH-LOGICAL-c430t-24f6f1d03d7dac13f8b3126a244666f123fb33dc9fbdd42144fb8d94bf134cda3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/30086749$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/30086749$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,799,23909,23910,25118,27901,27902,57992,58225</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19895478$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17940943$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Colebunders, Robert</creatorcontrib><creatorcontrib>Tshomba, Antoine</creatorcontrib><creatorcontrib>Van Kerkhove, Maria D.</creatorcontrib><creatorcontrib>Bausch, Daniel G.</creatorcontrib><creatorcontrib>Campbell, Pat</creatorcontrib><creatorcontrib>Libande, Modeste</creatorcontrib><creatorcontrib>Pirard, Patricia</creatorcontrib><creatorcontrib>Tshioko, Florimond</creatorcontrib><creatorcontrib>Mardel, Simon</creatorcontrib><creatorcontrib>Mulangu, Sabue</creatorcontrib><creatorcontrib>Sleurs, Hilde</creatorcontrib><creatorcontrib>Rollin, Pierre E.</creatorcontrib><creatorcontrib>Muyembe-Tamfum, Jean-Jacques</creatorcontrib><creatorcontrib>Jeffs, Benjamin</creatorcontrib><creatorcontrib>Borchert, Matthias</creatorcontrib><creatorcontrib>International Scientific and Technical Committee "DRC Watsa/Durba 1999 Marburg Outbreak Investigation Group"</creatorcontrib><creatorcontrib>International Scientific and Technical Committee "DRC Watsa/Durba 1999 Marburg Outbreak Investigation Group"</creatorcontrib><creatorcontrib>International Scientific and Technical Committee “DRC Watsa/Durba 1999 Marburg Outbreak Investigation Group”</creatorcontrib><title>Marburg Hemorrhagic Fever in Durba and Watsa, Democratic Republic of the Congo: Clinical Documentation, Features of Illness, and Treatment</title><title>The Journal of infectious diseases</title><addtitle>The Journal of Infectious Diseases</addtitle><description>The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initial symptoms included fever, headache, general pain, nausea, vomiting, and anorexia (median day of onset, day 1–2), followed by hemorrhagic manifestations (day 5–8+), and terminal symptoms included confusion, agitation, coma, anuria, and shock. Treatment in isolation wards was acceptable, but the quality of clinical documentation was unsatisfactory. Improved clinical documentation is necessary for a basic evaluation of supportive treatment.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Democratic Republic of the Congo - epidemiology</subject><subject>Diarrhea</subject><subject>Disease outbreaks</subject><subject>Disease Progression</subject><subject>Documentation</subject><subject>Epidemiology and Outbreak Management</subject><subject>Female</subject><subject>Fever</subject><subject>Headache</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Marburg disease, ebola disease</subject><subject>Marburg virus</subject><subject>Marburg virus disease</subject><subject>Marburg Virus Disease - epidemiology</subject><subject>Marburg Virus Disease - mortality</subject><subject>Marburg Virus Disease - physiopathology</subject><subject>Marburgvirus</subject><subject>Medical Records</subject><subject>Medical sciences</subject><subject>Pain</subject><subject>Retrospective Studies</subject><subject>Survival Rate</subject><subject>Symptoms</subject><subject>Tropical medicine</subject><subject>Tropical viral diseases</subject><subject>Viral diseases</subject><subject>Vomiting</subject><issn>0022-1899</issn><issn>1537-6613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0ctuEzEUBmALgWgo8AYgb2CVAd_GHneHEkoqCohSKGJjeXxJp8zYwZ5B8Ao8NQ6JmiUrH-n_9B_JB4DHGL3AqOEva4JqRu-AGa6pqDjH9C6YIURIhRspj8CDnG8QQoxycR8cYSEZkozOwJ93OrVTWsOVG2JK13rdGXjqfroEuwCXU2o11MHCKz1mPYfLokzSY0EXbjO1fRmih-O1g4sY1vEELvoudEb3cBnNNLgwFhzDvHTqcUoub_lZ3weX8_xf82UqyRY-BPe87rN7tH-PwefT15eLVXX-4c3Z4tV5ZRhFY0WY5x5bRK2w2mDqm5ZiwjVhjPOSEOpbSq2RvrWWEcyYbxsrWesxZcZqegye73o3Kf6YXB7V0GXj-l4HF6eseMMQI0L8FxIkcV32HaBJMefkvNqkbtDpt8JIbc-jducp8Om-cWoHZw9sf48Cnu2BzuUTfdLBdPngZCNrJprinuzcTR5jus0pKssEkyWvdnmXR_frNtfpu-KCilqtvn5T8tPHt--vvlwoSv8C-3KvzQ</recordid><startdate>20071115</startdate><enddate>20071115</enddate><creator>Colebunders, Robert</creator><creator>Tshomba, Antoine</creator><creator>Van Kerkhove, Maria D.</creator><creator>Bausch, Daniel G.</creator><creator>Campbell, Pat</creator><creator>Libande, Modeste</creator><creator>Pirard, Patricia</creator><creator>Tshioko, Florimond</creator><creator>Mardel, Simon</creator><creator>Mulangu, Sabue</creator><creator>Sleurs, Hilde</creator><creator>Rollin, Pierre E.</creator><creator>Muyembe-Tamfum, Jean-Jacques</creator><creator>Jeffs, Benjamin</creator><creator>Borchert, Matthias</creator><general>The University of Chicago Press</general><general>University of Chicago Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20071115</creationdate><title>Marburg Hemorrhagic Fever in Durba and Watsa, Democratic Republic of the Congo: Clinical Documentation, Features of Illness, and Treatment</title><author>Colebunders, Robert ; Tshomba, Antoine ; Van Kerkhove, Maria D. ; Bausch, Daniel G. ; Campbell, Pat ; Libande, Modeste ; Pirard, Patricia ; Tshioko, Florimond ; Mardel, Simon ; Mulangu, Sabue ; Sleurs, Hilde ; Rollin, Pierre E. ; Muyembe-Tamfum, Jean-Jacques ; Jeffs, Benjamin ; Borchert, Matthias</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-24f6f1d03d7dac13f8b3126a244666f123fb33dc9fbdd42144fb8d94bf134cda3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Democratic Republic of the Congo - 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subjects | Animals Biological and medical sciences Democratic Republic of the Congo - epidemiology Diarrhea Disease outbreaks Disease Progression Documentation Epidemiology and Outbreak Management Female Fever Headache Human viral diseases Humans Infectious diseases Male Marburg disease, ebola disease Marburg virus Marburg virus disease Marburg Virus Disease - epidemiology Marburg Virus Disease - mortality Marburg Virus Disease - physiopathology Marburgvirus Medical Records Medical sciences Pain Retrospective Studies Survival Rate Symptoms Tropical medicine Tropical viral diseases Viral diseases Vomiting |
title | Marburg Hemorrhagic Fever in Durba and Watsa, Democratic Republic of the Congo: Clinical Documentation, Features of Illness, and Treatment |
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