Marburg Hemorrhagic Fever in Durba and Watsa, Democratic Republic of the Congo: Clinical Documentation, Features of Illness, and Treatment

The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initia...

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Veröffentlicht in:The Journal of infectious diseases 2007-11, Vol.196 (Supplement-2), p.S148-S153
Hauptverfasser: Colebunders, Robert, Tshomba, Antoine, Van Kerkhove, Maria D., Bausch, Daniel G., Campbell, Pat, Libande, Modeste, Pirard, Patricia, Tshioko, Florimond, Mardel, Simon, Mulangu, Sabue, Sleurs, Hilde, Rollin, Pierre E., Muyembe-Tamfum, Jean-Jacques, Jeffs, Benjamin, Borchert, Matthias
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container_end_page S153
container_issue Supplement-2
container_start_page S148
container_title The Journal of infectious diseases
container_volume 196
creator Colebunders, Robert
Tshomba, Antoine
Van Kerkhove, Maria D.
Bausch, Daniel G.
Campbell, Pat
Libande, Modeste
Pirard, Patricia
Tshioko, Florimond
Mardel, Simon
Mulangu, Sabue
Sleurs, Hilde
Rollin, Pierre E.
Muyembe-Tamfum, Jean-Jacques
Jeffs, Benjamin
Borchert, Matthias
description The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initial symptoms included fever, headache, general pain, nausea, vomiting, and anorexia (median day of onset, day 1–2), followed by hemorrhagic manifestations (day 5–8+), and terminal symptoms included confusion, agitation, coma, anuria, and shock. Treatment in isolation wards was acceptable, but the quality of clinical documentation was unsatisfactory. Improved clinical documentation is necessary for a basic evaluation of supportive treatment.
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subjects Animals
Biological and medical sciences
Democratic Republic of the Congo - epidemiology
Diarrhea
Disease outbreaks
Disease Progression
Documentation
Epidemiology and Outbreak Management
Female
Fever
Headache
Human viral diseases
Humans
Infectious diseases
Male
Marburg disease, ebola disease
Marburg virus
Marburg virus disease
Marburg Virus Disease - epidemiology
Marburg Virus Disease - mortality
Marburg Virus Disease - physiopathology
Marburgvirus
Medical Records
Medical sciences
Pain
Retrospective Studies
Survival Rate
Symptoms
Tropical medicine
Tropical viral diseases
Viral diseases
Vomiting
title Marburg Hemorrhagic Fever in Durba and Watsa, Democratic Republic of the Congo: Clinical Documentation, Features of Illness, and Treatment
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