Correlation of levels and patterns of genomic instability with histological grading of DCIS

Histological grading of ductal carcinoma-in-situ (DCIS) lesions separates DCIS into three subgroups (well-, moderately, or poorly differentiated). It is unclear, however, whether breast disease progresses along a histological continuum or whether each grade represents a separate disease. In this stu...

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Veröffentlicht in:	Annals of surgical oncology 2007-11, Vol.14 (11), p.3070-3077
Hauptverfasser:	Ellsworth, Rachel E, Ellsworth, Darrell L, Love, Brad, Patney, Heather L, Hoffman, Laurel R, Kane, Jennifer, Hooke, Jeffrey A, Shriver, Craig D
Format:	Artikel
Sprache:	eng
Schlagworte:	Allelic Imbalance Breast Neoplasms - diagnosis Breast Neoplasms - genetics Carcinoma, Ductal, Breast - diagnosis Carcinoma, Ductal, Breast - genetics Carcinoma, Intraductal, Noninfiltrating - diagnosis Carcinoma, Intraductal, Noninfiltrating - genetics Chromosome Aberrations Chromosome Mapping Chromosomes, Human - ultrastructure DNA - genetics DNA, Neoplasm - genetics DNA, Neoplasm - metabolism Female Genomic Instability Humans Middle Aged Prevalence Prognosis
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