Antifungal Effect of Eugenol and Nerolidol against Microsporum gypseum in a Guinea Pig Model

Essential oils have been widely used in anti-infectious application. In the present study, we elucidated the antifungal activities of eugenol and nerolidol isolated from Japanese cypress oil in a guinea pig model infected by Microsporum gypseum (M. gypseum). A minimal inhibitory concentration (MIC),...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2007, Vol.30(1), pp.184-188
Hauptverfasser:	Lee, Sook-Jin, Han, Je-Ik, Lee, Geun-Shik, Park, Mi-Jin, Choi, In-Gyu, Na, Ki-Jeong, Jeung, Eui-Bae
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antifungal activity Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Antifungal Agents - therapeutic use Cupressus Cupressus - chemistry Dermatomycoses - drug therapy Dermatomycoses - microbiology Dermatomycoses - pathology Disease Models, Animal eugenol Eugenol - isolation & purification Eugenol - pharmacology Eugenol - therapeutic use guinea pig Guinea Pigs Hair - drug effects Hair - microbiology Male Microbial Sensitivity Tests Microsporum - drug effects Microsporum - growth & development Microsporum - isolation & purification Microsporum gypseum nerolidol Oils, Volatile - chemistry Sesquiterpenes - isolation & purification Sesquiterpenes - pharmacology Sesquiterpenes - therapeutic use Skin - drug effects Skin - microbiology Skin - pathology Time Factors
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