Requirement of Pygopus 2 in breast cancer

The development of novel therapeutic strategies for breast cancer requires the identification of molecular targets involved in malignancy. Human Pygopus (Pygo)-1 and -2 are recently discovered components of the Wnt signaling pathway required for beta-Catenin/Tcf dependent transcription in embryos an...

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Veröffentlicht in:	International journal of oncology 2007-02, Vol.30 (2), p.357-363
Hauptverfasser:	ANDREWS, Phillip G. P, LAKE, Blue B, POPADIUK, Catherine, KAO, Kenneth R
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blotting, Western Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Line, Tumor Cell Nucleus - metabolism Cell Proliferation Cyclin D1 - metabolism Cytoskeletal Proteins Gene Expression Regulation, Neoplastic Gynecology. Andrology. Obstetrics Humans Intracellular Signaling Peptides and Proteins - metabolism Intracellular Signaling Peptides and Proteins - physiology Mammary gland diseases Medical sciences Oligonucleotides, Antisense - chemistry RNA - chemistry RNA, Messenger - metabolism Signal Transduction Transfection Tumors
Online-Zugang:	Volltext
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