Direct N-Cyclopropylation of Cyclic Amides and Azoles Employing a Cyclopropylbismuth Reagent

Cyclopropanes are commonly found in medicinal chemistry since they provide unique spatial and electronic features, combined with high metabolic stability in liver microsomes. Although many methods are found in the chemist's arsenal to connect a cyclopropyl group to a carbon atom, none exist tha...

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Veröffentlicht in:	Journal of the American Chemical Society 2007-01, Vol.129 (1), p.44-45
Hauptverfasser:	Gagnon, Alexandre, St-Onge, Miguel, Little, Kelly, Duplessis, Martin, Barabé, Francis
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - chemistry Azoles - chemistry Cyclopropanes - chemical synthesis Cyclopropanes - chemistry Organometallic Compounds - chemical synthesis Organometallic Compounds - chemistry
Online-Zugang:	Volltext
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