Differential Regulation of Cytokine Release and Leukocyte Migration by Lipopolysaccharide-Stimulated Primary Human Lung Alveolar Type II Epithelial Cells and Macrophages

Bacterial colonization is a secondary feature of many lung disorders associated with elevated cytokine levels and increased leukocyte recruitment. We hypothesized that, alongside macrophages, the epithelium would be an important source of these mediators. We investigated the effect of LPS (0, 10, 10...

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Veröffentlicht in:Journal of Immunology 2007-01, Vol.178 (1), p.463-473
Hauptverfasser: Thorley, Andrew J, Ford, Paul A, Giembycz, Mark A, Goldstraw, Peter, Young, Alan, Tetley, Teresa D
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Sprache:eng
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