The Mechanosensitive Channel Protein MscL Is Targeted by the SRP to The Novel YidC Membrane Insertion Pathway of Escherichia coli

The mechanosensitive channel MscL in the inner membrane of Escherichia coli is a homopentameric complex involved in homeostasis when cells are exposed to hypo-osmotic conditions. The E. coli MscL protein is synthesized as a polypeptide of 136 amino acid residues and uses the bacterial signal recogni...

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Veröffentlicht in:	Journal of molecular biology 2007-01, Vol.365 (4), p.995-1004
Hauptverfasser:	Facey, Sandra J., Neugebauer, Stella A., Krauss, Susanne, Kuhn, Andreas
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism Bacterial Proteins - metabolism Cell Membrane - metabolism Chloroplasts - metabolism Electrochemistry - methods Escherichia coli Escherichia coli - metabolism Escherichia coli Proteins - chemistry Escherichia coli Proteins - metabolism Escherichia coli Proteins - physiology Evolution, Molecular Ion Channels - chemistry Ion Channels - physiology Membrane Potentials Membrane Transport Proteins - metabolism Mitochondria - metabolism MscL Plasmids - metabolism Protein Transport Proton-Motive Force Sec translocase SEC Translocation Channels Signal Recognition Particle SRP YidC
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