Hedgehog signaling pathway is a possible therapeutic target for gastric cancer

Background and Objectives It has been shown that the hedgehog (Hh) signaling pathway is activated in gastric cancer. To investigate the viability of the Hh pathway as a therapeutic target, we analyzed activation of the Hh pathway in gastric cancer. Methods Surgically resected gastric carcinoma speci...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of surgical oncology 2007-01, Vol.95 (1), p.55-62
Hauptverfasser:	Yanai, Kosuke, Nagai, Shuntaro, Wada, Junji, Yamanaka, Naoki, Nakamura, Masafumi, Torata, Nobuhiro, Noshiro, Hirokazu, Tsuneyoshi, Masazumi, Tanaka, Masao, Katano, Mitsuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - pathology Adenocarcinoma - secondary Adult Aged Aged, 80 and over Carcinoma, Signet Ring Cell - metabolism Carcinoma, Signet Ring Cell - pathology Carcinoma, Signet Ring Cell - secondary Cell Line, Tumor Female gastric cancer Gli1 Hedgehog Proteins - physiology hedgehog signaling histologic heterogeneity Humans lymph node metastasis Lymph Nodes - metabolism Lymph Nodes - pathology Lymphatic Metastasis Male Middle Aged Neoplasm Invasiveness Oncogene Proteins - analysis Oncogene Proteins - genetics Receptors, Cell Surface - metabolism Signal Transduction - physiology Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Trans-Activators - analysis Trans-Activators - genetics Trans-Activators - physiology Transcription Factors - metabolism Zinc Finger Protein GLI1
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!